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NCT00432744 · ClinicalTrials.gov registry record · Phase 3

Phase III Trial of Coenzyme Q10 in Mitochondrial Disease

A Phase 3 study of Mitochondrial Diseases, sponsored by University of Florida.

Completed
Registry status
Phase 3
Development phase
24
Enrollment target
3
Study locations

NCT00432744 is a Phase 3 study of Mitochondrial Diseases that has completed, run by University of Florida. The registered enrollment target is 24 participants, below the 273-participant average among 7 other Mitochondrial Diseases trials with a reported enrollment target (91% lower). The trial reports 3 study locations across 2 states.

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The verdict

NCT00432744, a Phase 3 study of Mitochondrial Diseases, has completed, sponsored by University of Florida.

COMPLETED
Registry status
Phase 3
Development phase
24 participants
Enrollment target
3
Study locations

Study Summary

To show that oral CoQ10 is a safe and effective treatment for children with inborn errors of mitochondrial energy metabolism due to defects in specific respiratory chain (RC) complexes or mitochondrial DNA (mtDNA) mutations, and that this beneficial action is reflected in improved motor and neurobehavioral function.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG CoenzymeQ10

Study Locations (3)

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati
  • Case Western Reserve University - Cleveland

Ontario

  • Hospital for Sick Children - Toronto

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2007-01
Est. Completion 2013-05
Phase Phase 3

Sponsor

University of Florida

1,106 total trials

What the Registry Record Tells You About NCT00432744

The ClinicalTrials.gov registry entry for NCT00432744 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 273-participant average among 7 other Mitochondrial Diseases trials with a reported enrollment target (91% lower). The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Mitochondrial Diseases appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00432744 reports 3 study locations spanning 2 distinct geographic areas - top geographies include Ohio, Ontario.

Frequently Asked Questions

What is clinical trial NCT00432744 about?

NCT00432744 is a clinical study titled "Phase III Trial of Coenzyme Q10 in Mitochondrial Disease". To show that oral CoQ10 is a safe and effective treatment for children with inborn errors of mitochondrial energy metabolism due to defects in specific respiratory chain (RC) complexes or mitochondrial DNA (mtDNA) mutations, and that this beneficial action is reflected in improved motor and neurobeh...

What is the current status of trial NCT00432744?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 24 participants. The study started on 2007-01. Estimated completion is 2013-05.

What conditions does trial NCT00432744 study?

This clinical trial studies the following conditions: Mitochondrial Diseases.

What interventions are being tested in trial NCT00432744?

The interventions under investigation include: Placebo (DRUG), CoenzymeQ10 (DRUG).

Who is sponsoring clinical trial NCT00432744?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00432744 being conducted?

This trial has 3 study locations across Ohio, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.