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NCT00427557 · ClinicalTrials.gov registry record · Phase 2
Cellular Therapy With Cord Blood Cells
A Phase 2 study, sponsored by M.D. Anderson Cancer Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 31
- Enrollment target
NCT00427557: Completed Phase 2 study, sponsored by M.D. Anderson Cancer Center.
NCT00427557 is a Phase 2 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 31 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00427557, a Phase 2 study, has completed, sponsored by M.D. Anderson Cancer Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 31 participants
- Enrollment target
Study Summary
The goal of this clinical research study is to learn if giving umbilical cord blood along with standard stem cells after high-dose chemotherapy will improve the response to a stem cell transplant. The safety of this treatment will also be studied.
Primary Outcome
Engraftment defined as first of three (3) consecutive days with Absolute neutrophil count (ANC) equal to or more than 0.5 \* 10\^9/L; assessed from baseline to 100 days post-engraftment.
Interventions
- DRUG Fludarabine
- DRUG Melphalan
- DRUG Rituximab
- PROCEDURE Umbilical Cord Blood
- OTHER Peripheral Blood Stem Cell Infusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2006-10 |
| Est. Completion | 2010-11 |
| Phase | Phase 2 |
What the finished NCT00427557 record still lists
NCT00427557 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 5 interventions - of which Fludarabine is the first listed.
NCT00427557 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00427557 about?
NCT00427557 is a clinical study titled "Cellular Therapy With Cord Blood Cells". The goal of this clinical research study is to learn if giving umbilical cord blood along with standard stem cells after high-dose chemotherapy will improve the response to a stem cell transplant. The safety of this treatment will also be studied.
What is the current status of trial NCT00427557?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 31 participants. The study started on 2006-10. Estimated completion is 2010-11.
What interventions are being tested in trial NCT00427557?
The interventions under investigation include: Fludarabine (DRUG), Melphalan (DRUG), Rituximab (DRUG), Umbilical Cord Blood (PROCEDURE), Peripheral Blood Stem Cell Infusion (OTHER).
Who is sponsoring clinical trial NCT00427557?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00427557's enrollment target sits among peer trials
31 1578th of 2000 higher than 419 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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