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NCT00425386 · ClinicalTrials.gov registry record · Phase 2

Sunitinib and Erlotinib in Treating Patients With Unresectable or Metastatic Kidney Cancer

A Phase 2 study of Kidney Cancer, sponsored by OHSU Knight Cancer Institute.

Completed
Registry status
Phase 2
Development phase
60
Enrollment target
4
Study locations

NCT00425386 is a Phase 2 study of Kidney Cancer that has completed, run by OHSU Knight Cancer Institute. The registered enrollment target is 60 participants, below the 879-participant average among 60 other Kidney Cancer trials with a reported enrollment target (93% lower). The trial reports 4 study locations across 2 states.

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The verdict

NCT00425386, a Phase 2 study of Kidney Cancer, has completed, sponsored by OHSU Knight Cancer Institute.

COMPLETED
Registry status
Phase 2
Development phase
60 participants
Enrollment target
4
Study locations

Study Summary

RATIONALE: Sunitinib and erlotinib may stop the growth of tumor cell by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving sunitinib together with erlotinib may kill more tumor cells. PURPOSE: This phase II trial is studying the best dose of erlotinib when given together with sunitinib and to see how well they work in treating patients with unresectable or metastatic kidney cancer.

Conditions Studied

Interventions

  • PROCEDURE biopsy
  • DRUG erlotinib hydrochloride
  • DRUG sunitinib malate

Study Locations (4)

Oregon

  • Providence Cancer Center at Providence Portland Medical Center - Portland
  • OHSU Knight Cancer Institute - Portland
  • Salem Hospital - Salem

California

  • University of Southern California - Los Angeles

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2006-08
Est. Completion 2014-03
Phase Phase 2

Sponsor

OHSU Knight Cancer Institute

211 total trials

What the Registry Record Tells You About NCT00425386

The ClinicalTrials.gov registry entry for NCT00425386 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 879-participant average among 60 other Kidney Cancer trials with a reported enrollment target (93% lower). The listed sponsor is OHSU Knight Cancer Institute, which has 211 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Kidney Cancer appearing as the primary indexed condition, and to 3 interventions - of which biopsy is the first listed.

NCT00425386 reports 4 study locations spanning 2 distinct geographic areas - top geographies include Oregon, California.

Frequently Asked Questions

What is clinical trial NCT00425386 about?

NCT00425386 is a clinical study titled "Sunitinib and Erlotinib in Treating Patients With Unresectable or Metastatic Kidney Cancer". RATIONALE: Sunitinib and erlotinib may stop the growth of tumor cell by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving sunitinib together with erlotinib may kill more tumor cells. PURPOSE: This phase II trial is studying the best dose of erlotini...

What is the current status of trial NCT00425386?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2006-08. Estimated completion is 2014-03.

What conditions does trial NCT00425386 study?

This clinical trial studies the following conditions: Kidney Cancer.

What interventions are being tested in trial NCT00425386?

The interventions under investigation include: biopsy (PROCEDURE), erlotinib hydrochloride (DRUG), sunitinib malate (DRUG).

Who is sponsoring clinical trial NCT00425386?

This trial is sponsored by OHSU Knight Cancer Institute, which has 211 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00425386 being conducted?

This trial has 4 study locations across California, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.