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NCT00410566 · ClinicalTrials.gov registry record · Phase 1
Safety Study of rhASM Enzyme Replacement Therapy in Adults With Acid Sphingomyelinase Deficiency (Niemann-Pick Disease)
A Phase 1 study, sponsored by Genzyme, a Sanofi Company.
- Terminated
- Registry status
- Phase 1
- Development phase
- 11
- Enrollment target
NCT00410566: Clinical Trial Phase 1 study, sponsored by Genzyme, a Sanofi Company.
NCT00410566 is a Phase 1 study that was terminated before completion, run by Genzyme, a Sanofi Company. The registered enrollment target is 11 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00410566, a Phase 1 study, was terminated before completion, sponsored by Genzyme, a Sanofi Company.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 11 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the safe range of single doses of rhASM administered to adults with ASM deficiency.
Interventions
- DRUG rhASM
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2006-12 |
| Est. Completion | 2009-04 |
| Phase | Phase 1 |
Why NCT00410566 stopped before completion
NCT00410566 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 1 intervention - of which rhASM is the first listed.
NCT00410566 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00410566 about?
NCT00410566 is a clinical study titled "Safety Study of rhASM Enzyme Replacement Therapy in Adults With Acid Sphingomyelinase Deficiency (Niemann-Pick Disease)". The purpose of this study is to determine the safe range of single doses of rhASM administered to adults with ASM deficiency.
What is the current status of trial NCT00410566?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2006-12. Estimated completion is 2009-04.
What interventions are being tested in trial NCT00410566?
The interventions under investigation include: rhASM (DRUG).
Who is sponsoring clinical trial NCT00410566?
This trial is sponsored by Genzyme, a Sanofi Company, which has 196 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00410566's enrollment target sits among peer trials
11 1911th of 2000 higher than 88 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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