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NCT00410475 · ClinicalTrials.gov registry record
Cancer Risk in X-Ray Technologists: Second Survey
A clinical trial, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- 146,022
- Enrollment target
NCT00410475: Completed study, sponsored by National Cancer Institute (NCI).
NCT00410475 is a clinical trial that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 146,022 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00410475 has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- 146,022 participants
- Enrollment target
Study Summary
Researchers at the National Cancer Institute and the University of Minnesota have followed a nationwide cohort of 146,022 radiologic technologists since 1982 (Boice 1992; Doody 1998; Mohan 2003; Sigurdson 2003). This is one of the largest cohorts of medical radiation workers studied to date (Yoshinaga 2003)and the only one with substantial numbers of women (73% female), extensive covariate data, both incident and death outcomes, and estimated occupational radiation doses. The overall study objectives are to: quantify radiation dose-response for cancers of the breast, thyroid, and other radiogenic sites; assess cancer risks associated with genotypic, phenotypic, or other biologically measurable factors; and determine if genetic variation modifies radiation-related cancer risks. More than 110,000 technologists completed at least one of three comprehensive questionnaire surveys administered over the last 20 years and 18,500 are deceased. The First Survey was mailed during 1984-1989 to 132,454 known living radiologic technologists, of whom 90,305 (68%) completed the survey (Boice 1992). The Second Survey was mailed during 1993-1998 to 126,628 known living technologists, of whom 90,972 (72%) completed the questionnaire (Sigurdson2003). Both surveys included detailed questions about employment as a radiologic technologist, family history of cancer, reproductive history, height, weight, other cancer risk factors (such as alcohol and tobacco use), history of personal diagnostic and therapeutic medical radiation procedures, and information on cancer and other health outcomes. A third follow-up of this cohort was recently completed. During 2003-2005, the Third Survey was mailed or administered by telephone to 101,694 living cohort members who had completed at least one of the two previous surveys; 73,838 technologists (73%) completed the survey. This questionnaire elicited information on medical outcomes to assess radiation-related risks, detailed calendar-specific employmen
Primary Outcome
Occupational ionizing radiation-related risks for cancer and other medical outcomes.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 146,022 participants |
| Start Date | 1997-09-17 |
| Est. Completion | 2020-03-31 |
What the finished NCT00410475 record still lists
NCT00410475 is an observational study that tracks outcomes without assigning an intervention. Its 146,022 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT00410475 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00410475 about?
NCT00410475 is a clinical study titled "Cancer Risk in X-Ray Technologists: Second Survey". Researchers at the National Cancer Institute and the University of Minnesota have followed a nationwide cohort of 146,022 radiologic technologists since 1982 (Boice 1992; Doody 1998; Mohan 2003; Sigurdson 2003). This is one of the largest cohorts of medical radiation workers studied to date (Yoshina...
What is the current status of trial NCT00410475?
This trial is currently completed. The enrollment target is 146,022 participants. The study started on 1997-09-17. Estimated completion is 2020-03-31.
Who is sponsoring clinical trial NCT00410475?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
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