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NCT00388414 · ClinicalTrials.gov registry record · NA

Imaging Study of Chronic Low Back Pain in Patients Taking Pain Medication

A NA study, sponsored by Stanford University.

Completed
Registry status
NA
Development phase
14
Enrollment target

NCT00388414: Completed NA study, sponsored by Stanford University.

NCT00388414 is a NA study that has completed, run by Stanford University. The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00388414, a NA study, has completed, sponsored by Stanford University.

COMPLETED
Registry status
NA
Development phase
14 participants
Enrollment target

Study Summary

Duloxetine has recently been shown to be effective in reducing the pain in chronic pain patients. Duloxetine is known to exert a central mechanism, however the precise human brain structures responsible for mediating its pain-relieving properties are not known. We will use functional magnetic resonance imaging (FMRI) to investigate the neural and functional correlates of pain.

Primary Outcome

Brief Pain Inventory (BPI) scores were obtained at baseline, weeks 1, 2, 6, 7, 8, and 12, and a follow-up visit one week after completing the study. Responses are rated on a scale from 0-10, with 0 = no pain and 10 = pain as bad as you can imagine. Placebo and duloxetine pain scores calculated by averaging pain scores from each visit after baseline. Values were converted to percent change in pain: \[(baseline pain - end point pain)/baseline pain\] x 100.

Interventions

  • DRUG Placebo
  • DRUG duloxetine

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2006-09
Est. Completion 2010-01
Phase NA
Stanford University

1,744 total trials

What the finished NCT00388414 record still lists

NCT00388414 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00388414 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00388414 about?

NCT00388414 is a clinical study titled "Imaging Study of Chronic Low Back Pain in Patients Taking Pain Medication". Duloxetine has recently been shown to be effective in reducing the pain in chronic pain patients. Duloxetine is known to exert a central mechanism, however the precise human brain structures responsible for mediating its pain-relieving properties are not known. We will use functional magnetic resona...

What is the current status of trial NCT00388414?

This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2006-09. Estimated completion is 2010-01.

What interventions are being tested in trial NCT00388414?

The interventions under investigation include: Placebo (DRUG), duloxetine (DRUG).

Who is sponsoring clinical trial NCT00388414?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00388414's enrollment target sits among peer trials

14 1909th of 2000 higher than 90 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00388414, the US trial registry maintained by the National Library of Medicine. NCT00388414 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.