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NCT00382473 · ClinicalTrials.gov registry record · NA
Mitochondrial Dysfunction in Type 2 Diabetes Mellitus and Capacity for Fat Oxidation During Exercise
A NA study, sponsored by University of Pittsburgh.
- Terminated
- Registry status
- NA
- Development phase
- 29
- Enrollment target
NCT00382473: Clinical Trial NA study, sponsored by University of Pittsburgh.
NCT00382473 is a NA study that was terminated before completion, run by University of Pittsburgh. The registered enrollment target is 29 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00382473, a NA study, was terminated before completion, sponsored by University of Pittsburgh.
- TERMINATED
- Registry status
- NA
- Development phase
- 29 participants
- Enrollment target
Study Summary
The purpose of this study is to compare the effects of an 8-week aerobic training program upon fat oxidation in vivo and markers of skeletal muscle mitochondrial content and oxidative capacity in sedentary obese subjects with and without type 2 diabetes. We will also investigate if mitochondrial content in muscle predicts success of weight loss. The specific aims are: * To compare systemic fat oxidation rates; * To measure mitochondrial content in muscle before and after aerobic training; * To determine if decreased mitochondrial content is also associated with decreased mitochondrial oxidative capacity; * To measure non-plasma fatty acid oxidation in vivo during submaximal exercise conditions both prior and after aerobic training; * To determine whether increases in fat oxidation due to physical activity predict weight loss success when a reduced calorie diet is added to a physical activity program.
Interventions
- BEHAVIORAL Aerobic exercise program - 8 weeks
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2006-09 |
| Est. Completion | 2010-12 |
| Phase | NA |
Why NCT00382473 stopped before completion
NCT00382473 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Aerobic exercise program - 8 weeks is the first listed.
NCT00382473 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00382473 about?
NCT00382473 is a clinical study titled "Mitochondrial Dysfunction in Type 2 Diabetes Mellitus and Capacity for Fat Oxidation During Exercise". The purpose of this study is to compare the effects of an 8-week aerobic training program upon fat oxidation in vivo and markers of skeletal muscle mitochondrial content and oxidative capacity in sedentary obese subjects with and without type 2 diabetes. We will also investigate if mitochondrial con...
What is the current status of trial NCT00382473?
This trial is currently terminated. It is a NA study. The enrollment target is 29 participants. The study started on 2006-09. Estimated completion is 2010-12.
What interventions are being tested in trial NCT00382473?
The interventions under investigation include: Aerobic exercise program - 8 weeks (BEHAVIORAL).
Who is sponsoring clinical trial NCT00382473?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00382473's enrollment target sits among peer trials
29 1702nd of 2000 higher than 297 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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