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NCT00382473 · ClinicalTrials.gov registry record · NA
Mitochondrial Dysfunction in Type 2 Diabetes Mellitus and Capacity for Fat Oxidation During Exercise
A NA study, sponsored by University of Pittsburgh.
- Terminated
- Registry status
- NA
- Development phase
- 29
- Enrollment target
NCT00382473 is a NA study that was terminated before completion, run by University of Pittsburgh. The registered enrollment target is 29 participants.
The verdict
NCT00382473, a NA study, was terminated before completion, sponsored by University of Pittsburgh.
- TERMINATED
- Registry status
- NA
- Development phase
- 29 participants
- Enrollment target
Study Summary
The purpose of this study is to compare the effects of an 8-week aerobic training program upon fat oxidation in vivo and markers of skeletal muscle mitochondrial content and oxidative capacity in sedentary obese subjects with and without type 2 diabetes. We will also investigate if mitochondrial content in muscle predicts success of weight loss. The specific aims are: * To compare systemic fat oxidation rates; * To measure mitochondrial content in muscle before and after aerobic training; * To determine if decreased mitochondrial content is also associated with decreased mitochondrial oxidative capacity; * To measure non-plasma fatty acid oxidation in vivo during submaximal exercise conditions both prior and after aerobic training; * To determine whether increases in fat oxidation due to physical activity predict weight loss success when a reduced calorie diet is added to a physical activity program.
Interventions
- BEHAVIORAL Aerobic exercise program - 8 weeks
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2006-09 |
| Est. Completion | 2010-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00382473
The ClinicalTrials.gov registry entry for NCT00382473 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Aerobic exercise program - 8 weeks is the first listed.
NCT00382473 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00382473 about?
NCT00382473 is a clinical study titled "Mitochondrial Dysfunction in Type 2 Diabetes Mellitus and Capacity for Fat Oxidation During Exercise". The purpose of this study is to compare the effects of an 8-week aerobic training program upon fat oxidation in vivo and markers of skeletal muscle mitochondrial content and oxidative capacity in sedentary obese subjects with and without type 2 diabetes. We will also investigate if mitochondrial con...
What is the current status of trial NCT00382473?
This trial is currently terminated. It is a NA study. The enrollment target is 29 participants. The study started on 2006-09. Estimated completion is 2010-12.
What interventions are being tested in trial NCT00382473?
The interventions under investigation include: Aerobic exercise program - 8 weeks (BEHAVIORAL).
Who is sponsoring clinical trial NCT00382473?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
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