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COMPLETED Phase 3

Effect of NovoTTF-100A in Recurrent Glioblastoma Multiforme (GBM)

NCT00379470 · View on ClinicalTrials.gov ↗

Study Summary

The study is a randomized, controlled trial, designed to test the efficacy and safety of a new medical device, the NovoTTF-100A. The device is an experimental, portable, battery operated device for chronic treatment of patients with recurrent or progressive glioblastoma multiforme (GBM) using alternating electric fields (termed TTFields).

Interventions

  • DEVICE NovoTTF-100A

Study Locations (20)

Other

  • University Hospital Graz — Graz
  • FN Brno - Masaryk University — Brno
  • Na Homolce Hospital — Prague
  • Hospital of Neurology Lyon - University Claude Bernard Lyon 1 — Lyon
  • Group Hospitals Pitie-Salpetriere — Paris

Illinois

  • Northwestern University — Chicago
  • University of Illinois in Chicago — Chicago
  • Evanston Northwestern Healthcare — Evanston

Massachusetts

  • Boston University Medical Center — Boston
  • Beth Israel Deaconess Medical Center — Boston
  • Lahey Clinic Medical Center — Burlington

New York

  • Memorial Sloan Kettering Cancer Center — New York
  • Weill Cornell Medical College — New York
  • Columbia University Medical Center — New York

Ohio

  • University Hospitals of Cleveland — Cleveland
  • Cleveland Clinic — Cleveland

New Jersey

  • NJ Neuroscience Institute - JFK Medical Center — Edison

Pennsylvania

  • University of Pittsburgh Medical Center (UPMC) — Pittsburgh

Virginia

  • University of Virginia — Charlottesville

Trial Details

FieldValue
Enrollment Target 236 participants
Start Date 2006-09
Est. Completion 2011-01
Phase Phase 3

Sponsor

NovoCure

32 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00379470

The ClinicalTrials.gov registry entry for NCT00379470 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 236 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is NovoCure, which has 32 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Recurrent Glioblastoma Multiforme appearing as the primary indexed condition, and to 1 intervention — of which NovoTTF-100A is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00379470 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Other, Illinois, Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00379470 about?

NCT00379470 is a clinical study titled "Effect of NovoTTF-100A in Recurrent Glioblastoma Multiforme (GBM)". The study is a randomized, controlled trial, designed to test the efficacy and safety of a new medical device, the NovoTTF-100A. The device is an experimental, portable, battery operated device for chronic treatment of patients with recurrent or progressive glioblastoma multiforme (GBM) using altern...

What is the current status of trial NCT00379470?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 236 participants. The study started on 2006-09. Estimated completion is 2011-01.

What conditions does trial NCT00379470 study?

This clinical trial studies the following conditions: Recurrent Glioblastoma Multiforme. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00379470?

The interventions under investigation include: NovoTTF-100A (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00379470?

This trial is sponsored by NovoCure, which has 32 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00379470 being conducted?

This trial has 20 study locations across Illinois, Massachusetts, New Jersey, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial