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RECRUITING Phase 4

Short Versus Standard of Care Antibiotic Duration for Children Hospitalized for CAP

NCT06494072 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this open label, randomized, non-inferiority clinical trial is to compare the treatment success of a 5 day antibiotic course versus a standard antibiotic course (usually 7-14 days of antibiotics) in hospitalized children aged 3 months to 18 years, with uncomplicated community acquired pneumonia. The main questions it aims to answer are: * Does a 5 day course work as well as standard (longer) courses of antibiotics for treating community acquired pneumonia in children? * Does a 5 day course cause less antibiotic side effects compared to a standard (longer) course of antibiotics in children with community acquired pneumonia? Participants will * be randomly assigned to either receive 5 total days or a total duration decided by the treating physician * receive a brief follow up questionnaire regarding clinical symptoms, follow up care/antibiotics, and side effects via phone or email at days 5 and 14 from the start of antibiotics Researchers will compare the experimental group (receiving 5 days duration) with the control group (standard duration) to see if 5 days is as successful as a standard duration.

Interventions

  • DRUG Amoxicillin
  • DRUG Ampicillin for Injection
  • DRUG Ceftriaxone for Injection
  • DRUG Ampicillin / Sulbactam Injection
  • DRUG Amoxicillin-clavulanate

Study Locations (1)

Wisconsin

  • Childrens Wisconsin — Milwaukee

Trial Details

FieldValue
Enrollment Target 236 participants
Start Date 2024-08-22
Est. Completion 2028-05
Phase Phase 4

Sponsor

Medical College of Wisconsin

614 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06494072

The ClinicalTrials.gov registry entry for NCT06494072 describes a study currently listed as recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 236 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical College of Wisconsin, which has 614 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Community Acquired Pneumonia in Children appearing as the primary indexed condition, and to 5 interventions — of which Amoxicillin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06494072 reports 1 study location spanning 1 distinct geographic area — top geographies include Wisconsin. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06494072 about?

NCT06494072 is a clinical study titled "Short Versus Standard of Care Antibiotic Duration for Children Hospitalized for CAP". The goal of this open label, randomized, non-inferiority clinical trial is to compare the treatment success of a 5 day antibiotic course versus a standard antibiotic course (usually 7-14 days of antibiotics) in hospitalized children aged 3 months to 18 years, with uncomplicated community acquired pn...

What is the current status of trial NCT06494072?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 236 participants. The study started on 2024-08-22. Estimated completion is 2028-05.

What conditions does trial NCT06494072 study?

This clinical trial studies the following conditions: Community Acquired Pneumonia in Children. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06494072?

The interventions under investigation include: Amoxicillin (DRUG), Ampicillin for Injection (DRUG), Ceftriaxone for Injection (DRUG), Ampicillin / Sulbactam Injection (DRUG), Amoxicillin-clavulanate (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06494072?

This trial is sponsored by Medical College of Wisconsin, which has 614 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06494072 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial