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NCT06494072 · ClinicalTrials.gov registry record · Phase 4
Short Versus Standard of Care Antibiotic Duration for Children Hospitalized for CAP
A Phase 4 study of Community Acquired Pneumonia in Children, sponsored by Medical College of Wisconsin.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 236
- Enrollment target
- 1
- Study location
NCT06494072: Recruiting Phase 4 study of Community Acquired Pneumonia in Children, sponsored by Medical College of Wisconsin.
NCT06494072 is a Phase 4 study of Community Acquired Pneumonia in Children that is actively recruiting participants, run by Medical College of Wisconsin. The registered enrollment target is 236 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (54% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06494072, a Phase 4 study of Community Acquired Pneumonia in Children, is actively recruiting participants, sponsored by Medical College of Wisconsin.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 236 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this open label, randomized, non-inferiority clinical trial is to compare the treatment success of a 5 day antibiotic course versus a standard antibiotic course (usually 7-14 days of antibiotics) in hospitalized children aged 3 months to 18 years, with uncomplicated community acquired pneumonia. The main questions it aims to answer are: * Does a 5 day course work as well as standard (longer) courses of antibiotics for treating community acquired pneumonia in children? * Does a 5 day course cause less antibiotic side effects compared to a standard (longer) course of antibiotics in children with community acquired pneumonia? Participants will * be randomly assigned to either receive 5 total days or a total duration decided by the treating physician * receive a brief follow up questionnaire regarding clinical symptoms, follow up care/antibiotics, and side effects via phone or email at days 5 and 14 from the start of antibiotics Researchers will compare the experimental group (receiving 5 days duration) with the control group (standard duration) to see if 5 days is as successful as a standard duration.
Primary Outcome
Treatment failure is defined as the clinical need for additional antibiotic treatment, an emergency department (ED) visit, or readmission to the hospital for a suspected lower respiratory tract infection within 14 days of treatment initiation.
Conditions Studied
Interventions
- DRUG Amoxicillin
- DRUG Ampicillin for Injection
- DRUG Ceftriaxone for Injection
- DRUG Ampicillin / Sulbactam Injection
- DRUG Amoxicillin-clavulanate
Study Locations (1)
Wisconsin
- Childrens Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 236 participants |
| Start Date | 2024-08-22 |
| Est. Completion | 2028-05 |
| Phase | Phase 4 |
What NCT06494072 shows while recruiting
NCT06494072 is an interventional study that assigns participants to a tested intervention. The registered 236 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (54% lower).
The record links to 1 condition, with Community Acquired Pneumonia in Children appearing as the primary indexed condition, and to 5 interventions - of which Amoxicillin is the first listed.
NCT06494072 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT06494072 about?
NCT06494072 is a clinical study titled "Short Versus Standard of Care Antibiotic Duration for Children Hospitalized for CAP". The goal of this open label, randomized, non-inferiority clinical trial is to compare the treatment success of a 5 day antibiotic course versus a standard antibiotic course (usually 7-14 days of antibiotics) in hospitalized children aged 3 months to 18 years, with uncomplicated community acquired pn...
What is the current status of trial NCT06494072?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 236 participants. The study started on 2024-08-22. Estimated completion is 2028-05.
What conditions does trial NCT06494072 study?
This clinical trial studies the following conditions: Community Acquired Pneumonia in Children.
What interventions are being tested in trial NCT06494072?
The interventions under investigation include: Amoxicillin (DRUG), Ampicillin for Injection (DRUG), Ceftriaxone for Injection (DRUG), Ampicillin / Sulbactam Injection (DRUG), Amoxicillin-clavulanate (DRUG).
Who is sponsoring clinical trial NCT06494072?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06494072 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06494072's enrollment target sits among peer trials
236 367th of 2000 higher than 1,633 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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