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NCT00377520 · ClinicalTrials.gov registry record · Phase 2

A Trial for Patients With Advanced/Recurrent Endometrial Cancer

A Phase 2 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 2
Development phase
27
Enrollment target

NCT00377520: Completed Phase 2 study, sponsored by Eli Lilly and Company.

NCT00377520 is a Phase 2 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 27 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00377520, a Phase 2 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 2
Development phase
27 participants
Enrollment target

Study Summary

The intent of this protocol is to screen a new agent for activity in patients with advanced or recurrent endometrial carcinoma. This phase II trial is studying how well pemetrexed disodium works in treating patients with advanced or recurrent endometrial carcinoma.

Primary Outcome

Best response recorded from the start of treatment until disease progression/recurrence using Response Evaluation Criteria In Solid Tumors (RECIST) criteria that defines when participants improve ("respond"), stay the same ("stable"), or worsen ("progression") during treatment. Complete response (CR) = disappearance of all target lesions; Partial response (PR) = 30% decrease in the sum of the longest diameter of target lesions; Progressive disease (PD) = 20% increase in the sum of the longest di

Interventions

  • DRUG pemetrexed

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2006-09
Est. Completion 2008-09
Phase Phase 2
Eli Lilly and Company

1,341 total trials

What the finished NCT00377520 record still lists

NCT00377520 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower).

The record links to 0 conditions, and to 1 intervention - of which pemetrexed is the first listed.

NCT00377520 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00377520 about?

NCT00377520 is a clinical study titled "A Trial for Patients With Advanced/Recurrent Endometrial Cancer". The intent of this protocol is to screen a new agent for activity in patients with advanced or recurrent endometrial carcinoma. This phase II trial is studying how well pemetrexed disodium works in treating patients with advanced or recurrent endometrial carcinoma.

What is the current status of trial NCT00377520?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2006-09. Estimated completion is 2008-09.

What interventions are being tested in trial NCT00377520?

The interventions under investigation include: pemetrexed (DRUG).

Who is sponsoring clinical trial NCT00377520?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00377520's enrollment target sits among peer trials

27 1697th of 2000 higher than 293 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00377520, the US trial registry maintained by the National Library of Medicine. NCT00377520 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.