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NCT00374296 · ClinicalTrials.gov registry record · Phase 2

MGCD0103 in Elderly Patients With Previously Untreated AML/High Risk MDS or Adults With Relapsed/Refractory Disease

A Phase 2 study, sponsored by Mirati Therapeutics.

Terminated
Registry status
Phase 2
Development phase
35
Enrollment target

NCT00374296: Clinical Trial Phase 2 study, sponsored by Mirati Therapeutics.

NCT00374296 is a Phase 2 study that was terminated before completion, run by Mirati Therapeutics. The registered enrollment target is 35 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00374296, a Phase 2 study, was terminated before completion, sponsored by Mirati Therapeutics.

TERMINATED
Registry status
Phase 2
Development phase
35 participants
Enrollment target

Study Summary

In this study, MGCD0103, a new anticancer drug under investigation, is given three times per week to elderly patients with previously untreated acute myelogenous leukemia/high risk myelodysplastic syndrome or adults with relapsed/refractory disease.

Interventions

  • DRUG MGCD0103

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2006-09
Est. Completion 2008-09
Phase Phase 2
Mirati Therapeutics

49 total trials

Why NCT00374296 stopped before completion

NCT00374296 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% lower).

The record links to 0 conditions, and to 1 intervention - of which MGCD0103 is the first listed.

NCT00374296 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00374296 about?

NCT00374296 is a clinical study titled "MGCD0103 in Elderly Patients With Previously Untreated AML/High Risk MDS or Adults With Relapsed/Refractory Disease". In this study, MGCD0103, a new anticancer drug under investigation, is given three times per week to elderly patients with previously untreated acute myelogenous leukemia/high risk myelodysplastic syndrome or adults with relapsed/refractory disease.

What is the current status of trial NCT00374296?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 35 participants. The study started on 2006-09. Estimated completion is 2008-09.

What interventions are being tested in trial NCT00374296?

The interventions under investigation include: MGCD0103 (DRUG).

Who is sponsoring clinical trial NCT00374296?

This trial is sponsored by Mirati Therapeutics, which has 49 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00374296's enrollment target sits among peer trials

35 1524th of 2000 higher than 462 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00374296, the US trial registry maintained by the National Library of Medicine. NCT00374296 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.