Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00371332 · ClinicalTrials.gov registry record · Phase 3
Effect of Adjunctive Treatment With Arestin on the Subgingival Microflora in Patients With Moderate to Advanced Periodontitis
A Phase 3 study of Periodontitis, sponsored by OraPharma.
- Completed
- Registry status
- Phase 3
- Development phase
- 128
- Enrollment target
- 5
- Study locations
NCT00371332: Completed Phase 3 study of Periodontitis, sponsored by OraPharma.
NCT00371332 is a Phase 3 study of Periodontitis that has completed, run by OraPharma. The registered enrollment target is 128 participants, above the 103-participant average among 11 other Periodontitis trials with a reported enrollment target (24% higher). The trial reports 5 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00371332, a Phase 3 study of Periodontitis, has completed, sponsored by OraPharma.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 128 participants
- Enrollment target
- 5
- Study locations
Study Summary
The purpose of this study is to measure the antimicrobial effects of Arestin in subjects with moderate to advanced periodontal disease
Conditions Studied
Interventions
- DRUG Minocycline HCL Microspheres
Study Locations (5)
California
- - Los Angeles
Maryland
- - Baltimore
Massachusetts
- - Boston
New York
- - Buffalo
Tennessee
- - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 128 participants |
| Start Date | 2004-01 |
| Phase | Phase 3 |
What the finished NCT00371332 record still lists
NCT00371332 is an interventional study that assigns participants to a tested intervention. The registered 128 participants enrollment target is mid-sized for trials with a published cap, above the 103-participant average among 11 other Periodontitis trials with a reported enrollment target (24% higher).
The record links to 1 condition, with Periodontitis appearing as the primary indexed condition, and to 1 intervention - of which Minocycline HCL Microspheres is the first listed.
NCT00371332 lists 5 locations in 5 states (California, Maryland, Massachusetts).
Frequently Asked Questions
What is clinical trial NCT00371332 about?
NCT00371332 is a clinical study titled "Effect of Adjunctive Treatment With Arestin on the Subgingival Microflora in Patients With Moderate to Advanced Periodontitis". The purpose of this study is to measure the antimicrobial effects of Arestin in subjects with moderate to advanced periodontal disease
What is the current status of trial NCT00371332?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 128 participants. The study started on 2004-01.
What conditions does trial NCT00371332 study?
This clinical trial studies the following conditions: Periodontitis.
What interventions are being tested in trial NCT00371332?
The interventions under investigation include: Minocycline HCL Microspheres (DRUG).
Who is sponsoring clinical trial NCT00371332?
This trial is sponsored by OraPharma, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00371332 being conducted?
This trial has 5 study locations across California, Maryland, Massachusetts, New York, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Periodontitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00371332's enrollment target sits among peer trials
128 6th of 11 higher than 6 of 11 other Periodontitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Periodontitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice
RECRUITING · Phase 3
-
The Use of a Non-Incised Minimally Invasive Flap Procedure in Conjunction With Emdogain® MI Compared to Traditional SRCP
RECRUITING · NA
-
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
RECRUITING · NA
-
An Evaluation of the Effect of the Erchonia FX-405 Laser as an Adjunctive Treatment of Periodontitis
RECRUITING · NA
-
Influence of SRP With MM on the Composition and Functional Characteristics of Subgingival Microbiome Communities
ACTIVE NOT RECRUITING · NA
-
Effectiveness of Scaling and Root Planing in Deeper Pockets
ACTIVE NOT RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02870738 · 128 participants · Phase 2
Bladder Directed vs. Pelvic Floor Therapy in IC/BPS
- NCT03294460 · 128 participants · Phase 1
Nicotinic Receptor Genetic Variation and Alcohol Reward
- NCT04149977 · 128 participants · NA
Blood Flow Restriction Therapy in Lower Limb Extensor Injuries
- NCT04373057 · 128 participants · Phase 1
Prebiotic Galacto-oligosaccharide and Acute GVHD
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia