Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00366145 · ClinicalTrials.gov registry record · Phase 3

Efficacy and Safety of Adult Human Mesenchymal Stem Cells to Treat Steroid Refractory Acute Graft Versus Host Disease (GVHD)

A Phase 3 study, sponsored by Mesoblast.

Completed
Registry status
Phase 3
Development phase
260
Enrollment target

NCT00366145 is a Phase 3 study that has completed, run by Mesoblast. The registered enrollment target is 260 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00366145, a Phase 3 study, has completed, sponsored by Mesoblast.

COMPLETED
Registry status
Phase 3
Development phase
260 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the efficacy and gather additional safety information for Prochymal® in participants who have failed to respond to steroid treatment of Grades B-D acute GVHD.

Interventions

  • DRUG Placebo
  • BIOLOGICAL Prochymal®
  • DRUG Standard of Care for GVHD

Trial Details

FieldValue
Enrollment Target 260 participants
Start Date 2006-08-17
Est. Completion 2009-05-28
Phase Phase 3

Sponsor

Mesoblast

25 total trials

What the Registry Record Tells You About NCT00366145

The ClinicalTrials.gov registry entry for NCT00366145 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 260 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mesoblast, which has 25 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT00366145 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00366145 about?

NCT00366145 is a clinical study titled "Efficacy and Safety of Adult Human Mesenchymal Stem Cells to Treat Steroid Refractory Acute Graft Versus Host Disease (GVHD)". The purpose of this study is to evaluate the efficacy and gather additional safety information for Prochymal® in participants who have failed to respond to steroid treatment of Grades B-D acute GVHD.

What is the current status of trial NCT00366145?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 260 participants. The study started on 2006-08-17. Estimated completion is 2009-05-28.

What interventions are being tested in trial NCT00366145?

The interventions under investigation include: Placebo (DRUG), Prochymal® (BIOLOGICAL), Standard of Care for GVHD (DRUG).

Who is sponsoring clinical trial NCT00366145?

This trial is sponsored by Mesoblast, which has 25 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.