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NCT00363168 · ClinicalTrials.gov registry record · Phase 1
Ranibizumab in Hemorrhagic Choroidal Neovascularization Trial
A Phase 1 study of Choroidal Neovascularization, sponsored by Johns Hopkins University.
- Completed
- Registry status
- Phase 1
- Development phase
- 7
- Enrollment target
- 1
- Study location
NCT00363168: Completed Phase 1 study of Choroidal Neovascularization, sponsored by Johns Hopkins University.
NCT00363168 is a Phase 1 study of Choroidal Neovascularization that has completed, run by Johns Hopkins University. The registered enrollment target is 7 participants, below the 185-participant average among 7 other Choroidal Neovascularization trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00363168, a Phase 1 study of Choroidal Neovascularization, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 7 participants
- Enrollment target
- 1
- Study location
Study Summary
This research is being done to look at the effects of an experimental drug, ranibizumab, on a condition called "predominantly hemorrhagic subfoveal choroidal neovascularization (CNV)" due to wet age-related macular degeneration. A predominantly hemorrhagic CNV lesion is diagnosed when at least 50% of the choroidal neovascular lesion is occupied by blood under the retina. We want to find out if injections of ranibizumab into the eye will help patients with this condition.
Primary Outcome
Visual acuity measured prior to first treatment with ranibizumab and at 12 months following the first treatment were compared for each subject enrolled in the study. The 12 month follow-up visual acuity was subtracted from the baseline visual acuity. Avoiding a 15 or more letter loss in visual acuity was considered a successful outcome.
Conditions Studied
Interventions
- DRUG Ranibizumab
Study Locations (1)
Maryland
- The Wilmer Eye Institute at Johns Hopkins - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2006-08 |
| Est. Completion | 2009-05 |
| Phase | Phase 1 |
What the finished NCT00363168 record still lists
NCT00363168 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 185-participant average among 7 other Choroidal Neovascularization trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Choroidal Neovascularization appearing as the primary indexed condition, and to 1 intervention - of which Ranibizumab is the first listed.
NCT00363168 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00363168 about?
NCT00363168 is a clinical study titled "Ranibizumab in Hemorrhagic Choroidal Neovascularization Trial". This research is being done to look at the effects of an experimental drug, ranibizumab, on a condition called "predominantly hemorrhagic subfoveal choroidal neovascularization (CNV)" due to wet age-related macular degeneration. A predominantly hemorrhagic CNV lesion is diagnosed when at least 50% ...
What is the current status of trial NCT00363168?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2006-08. Estimated completion is 2009-05.
What conditions does trial NCT00363168 study?
This clinical trial studies the following conditions: Choroidal Neovascularization.
What interventions are being tested in trial NCT00363168?
The interventions under investigation include: Ranibizumab (DRUG).
Who is sponsoring clinical trial NCT00363168?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00363168 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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