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NCT00360815 · ClinicalTrials.gov registry record · NA

Diabetes Control and Complications Trial (DCCT)

A NA study, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Completed
Registry status
NA
Development phase
1,441
Enrollment target

NCT00360815 is a NA study that has completed, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 1,441 participants.

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The verdict

NCT00360815, a NA study, has completed, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

COMPLETED
Registry status
NA
Development phase
1,441 participants
Enrollment target

Study Summary

Background. Long-term microvascular and neurologic complications cause major morbidity and mortality in patients with insulin-dependent diabetes mellitus (IDDM). We examined whether intensive treatment with the goal of maintaining blood glucose concentrations close to the normal range could decrease the frequency and severity of these complications. Methods. A total of 1441 patients with IDDM -- 726 with no retinopathy at base line (the primary-prevention cohort) and 715 with mild retinopathy (the secondary-intervention cohort) were randomly assigned to intensive therapy administered either with an external insulin pump or by three or more daily insulin injections and guided by frequent blood glucose monitoring or to conventional therapy with one or two daily insulin injections. The patients were followed for a mean of 6.5 years, and the appearance and progression of retinopathy and other complications were assessed regularly.

Interventions

  • BEHAVIORAL Insulin

Trial Details

FieldValue
Enrollment Target 1,441 participants
Start Date 1983-08
Est. Completion 1993-04
Phase NA

What the Registry Record Tells You About NCT00360815

The ClinicalTrials.gov registry entry for NCT00360815 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 1,441 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Insulin is the first listed.

NCT00360815 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00360815 about?

NCT00360815 is a clinical study titled "Diabetes Control and Complications Trial (DCCT)". Background. Long-term microvascular and neurologic complications cause major morbidity and mortality in patients with insulin-dependent diabetes mellitus (IDDM). We examined whether intensive treatment with the goal of maintaining blood glucose concentrations close to the normal range could decrease...

What is the current status of trial NCT00360815?

This trial is currently completed. It is a NA study. The enrollment target is 1,441 participants. The study started on 1983-08. Estimated completion is 1993-04.

What interventions are being tested in trial NCT00360815?

The interventions under investigation include: Insulin (BEHAVIORAL).

Who is sponsoring clinical trial NCT00360815?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.