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NCT00357435 · ClinicalTrials.gov registry record
Studies in Families With Corneal Dystrophy or Other Inherited Corneal Diseases
A clinical trial of Corneal Disease and Corneal Dystrophies, Hereditary, sponsored by National Eye Institute (NEI).
- Completed
- Registry status
- 86
- Enrollment target
- 6
- Study locations
NCT00357435: Completed study of Corneal Disease and Corneal Dystrophies, Hereditary, sponsored by National Eye Institute (NEI).
NCT00357435 is a study of Corneal Disease and Corneal Dystrophies, Hereditary that has completed, run by National Eye Institute (NEI). The registered enrollment target is 86 participants. The trial reports 6 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00357435, a study of Corneal Disease and Corneal Dystrophies, Hereditary, has completed, sponsored by National Eye Institute (NEI).
- COMPLETED
- Registry status
- 86 participants
- Enrollment target
- 6
- Study locations
Study Summary
This study will explore the clinical and hereditary (genetic) features of corneal dystrophy and other inherited corneal disease. Corneal dystrophy is clouding of the cornea - the transparent part of the eye covering the iris and pupil that passes light to the back of the eye. When the cornea becomes cloudy, interfering with the passage of light, vision may be impaired or lost. Corneal problems may occur with vision problems alone, or with other problems, such as changes in facial appearance or bone or joint problems. A better understanding of these genetic conditions may help in the development of better diagnostic tests and methods of disease management. Patients with corneal dystrophies and related corneal disease and their family members may be eligible for this study. Participants will be drawn from patients enrolled in other studies of corneal dystrophy at the NEI and collaborating clinics. Participants will undergo the following tests and procedures: * Medical and surgical history * Verification of diagnosis * Construction of a family tree regarding familial vision problems * Complete eye examination, including dilation of the pupils and photography of the cornea, tests of color vision, field of vision, and the ability to see in the dark, and photographs of the eye. * Blood sample collection to identify the genes responsible for corneal disease and ascertain how they cause disease.
Conditions Studied
Study Locations (6)
Other
- Zhongshan Opthalmic Center - Guangzhou
- Seconda Universita degli - Naples
California
- Jules Stein Eye Institute, UCLA - Los Angeles
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Ohio
- Cleveland Clinic - Cleveland
Texas
- University of Texas, Houston - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 86 participants |
| Start Date | 2003-10-06 |
| Est. Completion | 2016-07-21 |
What the finished NCT00357435 record still lists
NCT00357435 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 86 participants, a relatively small participant target.
The record links to 2 conditions, with Corneal Disease appearing as the primary indexed condition, and to 0 interventions.
NCT00357435 lists 6 locations in 5 states (Other, California, Maryland).
Frequently Asked Questions
What is clinical trial NCT00357435 about?
NCT00357435 is a clinical study titled "Studies in Families With Corneal Dystrophy or Other Inherited Corneal Diseases". This study will explore the clinical and hereditary (genetic) features of corneal dystrophy and other inherited corneal disease. Corneal dystrophy is clouding of the cornea - the transparent part of the eye covering the iris and pupil that passes light to the back of the eye. When the cornea becomes...
What is the current status of trial NCT00357435?
This trial is currently completed. The enrollment target is 86 participants. The study started on 2003-10-06. Estimated completion is 2016-07-21.
What conditions does trial NCT00357435 study?
This clinical trial studies the following conditions: Corneal Disease, Corneal Dystrophies, Hereditary.
Who is sponsoring clinical trial NCT00357435?
This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00357435 being conducted?
This trial has 6 study locations across California, Maryland, Ohio, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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