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NCT00350402 · ClinicalTrials.gov registry record · Phase 2
Masked Faces in Parkinson Disease: Mechanism and Treatment
A Phase 2 study of Parkinson's Disease, sponsored by University of Florida.
- Completed
- Registry status
- Phase 2
- Development phase
- 44
- Enrollment target
- 1
- Study location
NCT00350402: Completed Phase 2 study of Parkinson's Disease, sponsored by University of Florida.
NCT00350402 is a Phase 2 study of Parkinson's Disease that has completed, run by University of Florida. The registered enrollment target is 44 participants, below the 635-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00350402, a Phase 2 study of Parkinson's Disease, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 44 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to examine the effectiveness of high intensity respiratory muscle strength training in treating blunted facial expression in people with Parkinson disease.
Primary Outcome
Primary outcome is change in entropy score from baseline to immediate completion of 4 week intervention. Entropy is a computer derived index of facial movement that is computed by quantifying changes in pixel intensity as the face moves over a series of video frames. Entropy values range from 0 up to 100. Higher scores reflect greater movement and expressivity (desired). In this condition ("off dopamine), entropy scores were obtained when participants were tested "off" their normal dopamine medi
Conditions Studied
Interventions
- BEHAVIORAL Respiratory muscle strength training
Study Locations (1)
Florida
- Cognitive Neuroscience Laboratory, L3-135, McKnight Brain Institute, University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2004-12 |
| Est. Completion | 2009-11 |
| Phase | Phase 2 |
What the finished NCT00350402 record still lists
NCT00350402 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 635-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Parkinson's Disease appearing as the primary indexed condition, and to 1 intervention - of which Respiratory muscle strength training is the first listed.
NCT00350402 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT00350402 about?
NCT00350402 is a clinical study titled "Masked Faces in Parkinson Disease: Mechanism and Treatment". The purpose of this study is to examine the effectiveness of high intensity respiratory muscle strength training in treating blunted facial expression in people with Parkinson disease.
What is the current status of trial NCT00350402?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2004-12. Estimated completion is 2009-11.
What conditions does trial NCT00350402 study?
This clinical trial studies the following conditions: Parkinson's Disease.
What interventions are being tested in trial NCT00350402?
The interventions under investigation include: Respiratory muscle strength training (BEHAVIORAL).
Who is sponsoring clinical trial NCT00350402?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00350402 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00350402's enrollment target sits among peer trials
44 91st of 158 higher than 68 of 158 other Parkinson's Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson's Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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