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NCT00316875 · ClinicalTrials.gov registry record · Phase 1

Lapatinib and Doxorubicin Hydrochloride Liposome in Treating Patients With Metastatic Breast Cancer

A Phase 1 study of Breast Cancer, sponsored by Northwestern University.

Completed
Registry status
Phase 1
Development phase
23
Enrollment target
1
Study location

NCT00316875 is a Phase 1 study of Breast Cancer that has completed, run by Northwestern University. The registered enrollment target is 23 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00316875, a Phase 1 study of Breast Cancer, has completed, sponsored by Northwestern University.

COMPLETED
Registry status
Phase 1
Development phase
23 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Lapatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as doxorubicin hydrochloride liposome work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving lapatinib together with doxorubicin hydrochloride liposome may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of doxorubicin hydrochloride liposome when given together with lapatinib in treating patients with metastatic breast cancer.

Conditions Studied

Interventions

  • DRUG Doxil
  • DRUG lapatinib ditosylate

Study Locations (1)

Illinois

  • Robert H. Lurie Comprehensive Cancer Center at Northwestern University - Chicago

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2006-05
Est. Completion 2011-08
Phase Phase 1

Sponsor

Northwestern University

1,209 total trials

What the Registry Record Tells You About NCT00316875

The ClinicalTrials.gov registry entry for NCT00316875 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Doxil is the first listed.

NCT00316875 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT00316875 about?

NCT00316875 is a clinical study titled "Lapatinib and Doxorubicin Hydrochloride Liposome in Treating Patients With Metastatic Breast Cancer". RATIONALE: Lapatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as doxorubicin hydrochloride liposome work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividi...

What is the current status of trial NCT00316875?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2006-05. Estimated completion is 2011-08.

What conditions does trial NCT00316875 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT00316875?

The interventions under investigation include: Doxil (DRUG), lapatinib ditosylate (DRUG).

Who is sponsoring clinical trial NCT00316875?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00316875 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.