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NCT00295919 · ClinicalTrials.gov registry record · Phase 1

N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma

A Phase 1 study, sponsored by New Approaches to Neuroblastoma Therapy Consortium.

Completed
Registry status
Phase 1
Development phase
80
Enrollment target

NCT00295919: Completed Phase 1 study, sponsored by New Approaches to Neuroblastoma Therapy Consortium.

NCT00295919 is a Phase 1 study that has completed, run by New Approaches to Neuroblastoma Therapy Consortium. The registered enrollment target is 80 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00295919, a Phase 1 study, has completed, sponsored by New Approaches to Neuroblastoma Therapy Consortium.

COMPLETED
Registry status
Phase 1
Development phase
80 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as fenretinide LXS, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase I trial is studying the side effects and best dose of fenretinide LXS in treating patients with recurrent, refractory, or persistent neuroblastoma.

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER pharmacological study
  • DRUG ketoconazole
  • DRUG fenretinide lipid matrix

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2005-12
Est. Completion 2015-05
Phase Phase 1

What the finished NCT00295919 record still lists

NCT00295919 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher).

The record links to 0 conditions, and to 4 interventions - of which laboratory biomarker analysis is the first listed.

NCT00295919 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00295919 about?

NCT00295919 is a clinical study titled "N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma". RATIONALE: Drugs used in chemotherapy, such as fenretinide LXS, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase I trial is studying the side effects and best dose of fenretinide LXS in treating patients wit...

What is the current status of trial NCT00295919?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2005-12. Estimated completion is 2015-05.

What interventions are being tested in trial NCT00295919?

The interventions under investigation include: laboratory biomarker analysis (OTHER), pharmacological study (OTHER), ketoconazole (DRUG), fenretinide lipid matrix (DRUG).

Who is sponsoring clinical trial NCT00295919?

This trial is sponsored by New Approaches to Neuroblastoma Therapy Consortium, which has 23 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00295919's enrollment target sits among peer trials

80 672nd of 2000 higher than 1,305 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00295919, the US trial registry maintained by the National Library of Medicine. NCT00295919 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.