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NCT00293150 · ClinicalTrials.gov registry record · Phase 4

Reversing Endothelial and Diastolic Dysfunction and Improving Collagen Turnover in Diastolic Heart Failure

A Phase 4 study, sponsored by The Cleveland Clinic.

Terminated
Registry status
Phase 4
Development phase
11
Enrollment target

NCT00293150: Clinical Trial Phase 4 study, sponsored by The Cleveland Clinic.

NCT00293150 is a Phase 4 study that was terminated before completion, run by The Cleveland Clinic. The registered enrollment target is 11 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00293150, a Phase 4 study, was terminated before completion, sponsored by The Cleveland Clinic.

TERMINATED
Registry status
Phase 4
Development phase
11 participants
Enrollment target

Study Summary

The principle aim is to determine the efficacy of eplerenone in patients with diastolic heart failure to reverse cardiac remodeling and to improve diastolic function.

Primary Outcome

Improved diastolic function

Interventions

  • DRUG Eplerenone

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2003-09
Est. Completion 2007-09
Phase Phase 4
The Cleveland Clinic

688 total trials

Why NCT00293150 stopped before completion

NCT00293150 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Eplerenone is the first listed.

NCT00293150 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00293150 about?

NCT00293150 is a clinical study titled "Reversing Endothelial and Diastolic Dysfunction and Improving Collagen Turnover in Diastolic Heart Failure". The principle aim is to determine the efficacy of eplerenone in patients with diastolic heart failure to reverse cardiac remodeling and to improve diastolic function.

What is the current status of trial NCT00293150?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 11 participants. The study started on 2003-09. Estimated completion is 2007-09.

What interventions are being tested in trial NCT00293150?

The interventions under investigation include: Eplerenone (DRUG).

Who is sponsoring clinical trial NCT00293150?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00293150's enrollment target sits among peer trials

11 1931st of 2000 higher than 61 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00293150, the US trial registry maintained by the National Library of Medicine. NCT00293150 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.