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NCT00290732 · ClinicalTrials.gov registry record · Phase 1

Liposomal Doxorubicin Before Mastectomy in Treating Women With Invasive Breast Cancer

A Phase 1 study of Breast Cancer, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target
2
Study locations

NCT00290732 is a Phase 1 study of Breast Cancer that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 20 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT00290732, a Phase 1 study of Breast Cancer, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target
2
Study locations

Study Summary

RATIONALE: Drugs used in chemotherapy, such as liposomal doxorubicin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy in different ways, such as into the breast ducts, may kill more tumor cells. Giving chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. PURPOSE: This phase I trial is studying the side effects and best dose of liposomal doxorubicin when given before mastectomy in treating women with invasive breast cancer.

Conditions Studied

Interventions

  • DRUG Intraductal arm
  • DRUG Intravenous arm

Study Locations (2)

Indiana

  • Indiana University Melvin and Bren Simon Cancer Center - Indianapolis

Maryland

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins - Baltimore

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2005-11
Est. Completion 2011-10
Phase Phase 1

What the Registry Record Tells You About NCT00290732

The ClinicalTrials.gov registry entry for NCT00290732 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Intraductal arm is the first listed.

NCT00290732 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Indiana, Maryland.

Frequently Asked Questions

What is clinical trial NCT00290732 about?

NCT00290732 is a clinical study titled "Liposomal Doxorubicin Before Mastectomy in Treating Women With Invasive Breast Cancer". RATIONALE: Drugs used in chemotherapy, such as liposomal doxorubicin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy in different ways, such as into the breast ducts, may kill more tumor cells. Giving chemo...

What is the current status of trial NCT00290732?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2005-11. Estimated completion is 2011-10.

What conditions does trial NCT00290732 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT00290732?

The interventions under investigation include: Intraductal arm (DRUG), Intravenous arm (DRUG).

Who is sponsoring clinical trial NCT00290732?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00290732 being conducted?

This trial has 2 study locations across Indiana, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.