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NCT00288093 · ClinicalTrials.gov registry record · Phase 1

3-AP and Radiation Therapy in Treating Patients With Stage III Pancreatic Cancer That Cannot Be Removed By Surgery

A Phase 1 study of Pancreatic Adenocarcinoma and Stage III Pancreatic Cancer AJCC v6 and v7, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
30
Enrollment target
1
Study location

NCT00288093 is a Phase 1 study of Pancreatic Adenocarcinoma and Stage III Pancreatic Cancer AJCC v6 and v7 that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 30 participants, below the 99,465-participant average among 62 other Pancreatic Adenocarcinoma trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00288093, a Phase 1 study of Pancreatic Adenocarcinoma and Stage III Pancreatic Cancer AJCC v6 and v7, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

This phase I trial is studying the side effects and best dose of 3-AP when given together with radiation therapy in treating patients with stage III pancreatic cancer that cannot be removed by surgery. 3-AP may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high-energy x-rays to kill tumor cells. 3-AP may make tumor cells more sensitive to radiation therapy. Giving 3-AP together with radiation therapy may kill more tumor cells.

Interventions

  • RADIATION 3-Dimensional Conformal Radiation Therapy
  • DRUG Triapine

Study Locations (1)

Ohio

  • Ohio State University Comprehensive Cancer Center - Columbus

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2006-12-20
Est. Completion 2012-12-28
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00288093

The ClinicalTrials.gov registry entry for NCT00288093 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 99,465-participant average among 62 other Pancreatic Adenocarcinoma trials with a reported enrollment target (100% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Pancreatic Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions - of which 3-Dimensional Conformal Radiation Therapy is the first listed.

NCT00288093 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT00288093 about?

NCT00288093 is a clinical study titled "3-AP and Radiation Therapy in Treating Patients With Stage III Pancreatic Cancer That Cannot Be Removed By Surgery". This phase I trial is studying the side effects and best dose of 3-AP when given together with radiation therapy in treating patients with stage III pancreatic cancer that cannot be removed by surgery. 3-AP may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. R...

What is the current status of trial NCT00288093?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2006-12-20. Estimated completion is 2012-12-28.

What conditions does trial NCT00288093 study?

This clinical trial studies the following conditions: Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v6 and v7.

What interventions are being tested in trial NCT00288093?

The interventions under investigation include: 3-Dimensional Conformal Radiation Therapy (RADIATION), Triapine (DRUG).

Who is sponsoring clinical trial NCT00288093?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00288093 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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