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A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in the United States
NCT07122193 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to assess the safety and efficacy of NT 201 compared with placebo in participants with moderate to severe platysma prominence. The study will be conducted in two periods: Main Period (MP) and Open label Extension Period (OLEX).
Conditions Studied
Interventions
- DRUG NT 201
- DRUG NT 201 Placebo
Study Locations (20)
Florida
- Merz Investigative Site — Aventura
- Merz Investigative Site — Boca Raton
- Merz Investigative Site — Bradenton
- Merz Investigative Site — Coral Gables
- Merz Investigative Site — Coral Gables
- Merz Investigative Site — West Palm Beach
California
- Merz Investigative Site — Encino
- Merz Investigative Site — Los Angeles
- Merz Investigative Site — Redondo Beach
- Merz Investigative Site — Santa Monica
- Merz Investigative Site — Vista
New York
- Merz Investigative Site — Mount Kisco
- Merz Investigative Site — New York
Arizona
- Merz Investigative Site — Scottsdale
Colorado
- Merz Investigative Site — Greenwood Village
Connecticut
- Merz Investigative Site — Westport
District of Columbia
- Merz Investigative Site — Washington D.C.
Georgia
- Merz Investigative Site — Alpharetta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2025-08-27 |
| Est. Completion | 2028-01 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07122193
The ClinicalTrials.gov registry entry for NCT07122193 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merz North America, which has 37 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 10 conditions, with Physiological Effects of Drugs appearing as the primary indexed condition, and to 2 interventions — of which NT 201 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07122193 reports 20 study locations spanning 10 distinct geographic areas — top geographies include Florida, California, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07122193 about?
NCT07122193 is a clinical study titled "A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in the United States". The purpose of this study is to assess the safety and efficacy of NT 201 compared with placebo in participants with moderate to severe platysma prominence. The study will be conducted in two periods: Main Period (MP) and Open label Extension Period (OLEX).
What is the current status of trial NCT07122193?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 300 participants. The study started on 2025-08-27. Estimated completion is 2028-01.
What conditions does trial NCT07122193 study?
This clinical trial studies the following conditions: Physiological Effects of Drugs, Peripheral Nervous System Agents, Molecular Mechanisms of Pharmacological Action, Neurotransmitter Agents, Neuromuscular Agents. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07122193?
The interventions under investigation include: NT 201 (DRUG), NT 201 Placebo (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07122193?
This trial is sponsored by Merz North America, which has 37 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07122193 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Connecticut, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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