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NCT00276744 · ClinicalTrials.gov registry record · Phase 2

Individualized Drug Treatment for Treating Patients With Pancreatic Cancer

A Phase 2 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Terminated
Registry status
Phase 2
Development phase
249
Enrollment target

NCT00276744: Clinical Trial Phase 2 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

NCT00276744 is a Phase 2 study that was terminated before completion, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 249 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (87% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00276744, a Phase 2 study, was terminated before completion, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

TERMINATED
Registry status
Phase 2
Development phase
249 participants
Enrollment target

Study Summary

RATIONALE: Treating tumor tissue in the laboratory with different drugs may help doctors find the best drug for treating individual patients with pancreatic cancer. PURPOSE: This phase II trial is studying an individualized drug treatment selection process, based on laboratory results, for treating patients with pancreatic cancer that can be removed by surgery.

Primary Outcome

Percentage of patients survived at 6 months for patients whose tumors were xenografted and treated in the mouse when treated with the most active agent identified in that model

Interventions

  • DRUG Gemcitabine
  • DRUG docetaxel
  • DRUG Erlotinib
  • BIOLOGICAL cetuximab
  • DRUG capecitabine

Trial Details

FieldValue
Enrollment Target 249 participants
Start Date 2005-10
Est. Completion 2010-04
Phase Phase 2

Why NCT00276744 stopped before completion

NCT00276744 is an interventional study that assigns participants to a tested intervention. The registered 249 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (87% higher).

The record links to 0 conditions, and to 5 interventions - of which Gemcitabine is the first listed.

NCT00276744 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00276744 about?

NCT00276744 is a clinical study titled "Individualized Drug Treatment for Treating Patients With Pancreatic Cancer". RATIONALE: Treating tumor tissue in the laboratory with different drugs may help doctors find the best drug for treating individual patients with pancreatic cancer. PURPOSE: This phase II trial is studying an individualized drug treatment selection process, based on laboratory results, for treating...

What is the current status of trial NCT00276744?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 249 participants. The study started on 2005-10. Estimated completion is 2010-04.

What interventions are being tested in trial NCT00276744?

The interventions under investigation include: Gemcitabine (DRUG), docetaxel (DRUG), Erlotinib (DRUG), cetuximab (BIOLOGICAL), capecitabine (DRUG).

Who is sponsoring clinical trial NCT00276744?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00276744's enrollment target sits among peer trials

249 233rd of 2000 higher than 1,767 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00276744, the US trial registry maintained by the National Library of Medicine. NCT00276744 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.