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NCT00272363 · ClinicalTrials.gov registry record
Clinical and Molecular Studies in Families With Glaucoma and Related Diseases
A clinical trial, sponsored by National Eye Institute (NEI).
- Completed
- Registry status
- 484
- Enrollment target
NCT00272363: Completed study, sponsored by National Eye Institute (NEI).
NCT00272363 is a clinical trial that has completed, run by National Eye Institute (NEI). The registered enrollment target is 484 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00272363 has completed, sponsored by National Eye Institute (NEI).
- COMPLETED
- Registry status
- 484 participants
- Enrollment target
Study Summary
This study will document the clinical and genetic features of glaucoma and related diseases, including normal tension glaucoma (NTG). Researchers would like to define genetic influences and eventually isolate the genes causing those diseases. Glaucoma is an important cause of vision loss in the United States and worldwide. The disease is marked by a wearing down of the retina and optic nerve, often associated with increased pressure in the eye. It is often an inherited trait. This study will involve between 250 and 2,000 patients over a 5-year period. It will examine the natural history of the genotype, or genetic makeup, of a person and the phenotype, that is, visible situations produced by the interaction of the genotype and one's environment. Patients 4 and older who have glaucoma or related diseases or whose family members have those diseases may be eligible for this study. They will complete a medical history for the doctors to verify the diagnosis, inquire about medical problems and surgical operations, and gather data about vision problems in a patient's family (by drawing a family tree). The complete eye examination may take several hours. Eye drops will be used to dilate, or enlarge, the pupils of patients' eyes, and the pupils will stay dilated for 4 to 6 hours. There may be some temporary glare in brightly lit areas, which can be reduced by wearing of sunglasses. Patients may experience some blurring of vision. There may be a localized allergic reaction to the medication used or an increase of pressure inside the eye. If that occurs, medication to control the reaction will be given. In addition, photographs of the retina and perhaps even the lens will be taken. For that procedure, eye drops will dilate the pupils of the eyes. The light that is involved with the specialized photography may cause some mild discomfort. Patients will undergo eye tests regarding color vision, field of vision, and ability to see the dark. Also, there will be a measurement of
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 484 participants |
| Start Date | 2005-12-29 |
| Est. Completion | 2016-07-29 |
What the finished NCT00272363 record still lists
NCT00272363 is an observational study that tracks outcomes without assigning an intervention. The registered 484 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00272363 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00272363 about?
NCT00272363 is a clinical study titled "Clinical and Molecular Studies in Families With Glaucoma and Related Diseases". This study will document the clinical and genetic features of glaucoma and related diseases, including normal tension glaucoma (NTG). Researchers would like to define genetic influences and eventually isolate the genes causing those diseases. Glaucoma is an important cause of vision loss in the Uni...
What is the current status of trial NCT00272363?
This trial is currently completed. The enrollment target is 484 participants. The study started on 2005-12-29. Estimated completion is 2016-07-29.
Who is sponsoring clinical trial NCT00272363?
This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.
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