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NCT00266513 · ClinicalTrials.gov registry record
Studies of Disorders in Antibody Production and Related Primary Immunodeficiency States
A clinical trial, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Terminated
- Registry status
- 119
- Enrollment target
NCT00266513: Clinical Trial study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
NCT00266513 is a clinical trial that was terminated before completion, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 119 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00266513 was terminated before completion, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- TERMINATED
- Registry status
- 119 participants
- Enrollment target
Study Summary
This study investigates gene abnormalities in Primary Immune Deficiency(PID) with a goal of improving the diagnosis and treatment of patients. The specific disorders include: 1. X linked hyper IgM Syndrome which is caused by an abnormality in the CD40L gene. 2. NEMO associated immune deficiency which is caused by an abnormality in a gene called NEMO. 3. Common variable immunodeficiency (CVID) which has an unknown genetic basis. 4. Other disorders of immunoglobulin production. This study will: 1. Better characterize the clinical features of CD40 L deficiency and NEMO associated immune deficiency and other related primary immune deficiency syndromes. 2. Determine the frequency of CD40 L and Nemo abnormalities. 3. Determine whether particular abnormalities in these genes are associated with more of less severe illness or with specific symptoms. 4. Explore the basic mechanism by which these altered genes cause immune dysfunction. 5. Identify other genes causing low immune globulin levels and related primary immune deficient states.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 119 participants |
| Start Date | 2005-12-14 |
| Est. Completion | 2013-07-11 |
Why NCT00266513 stopped before completion
NCT00266513 is an observational study that tracks outcomes without assigning an intervention. The registered 119 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00266513 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00266513 about?
NCT00266513 is a clinical study titled "Studies of Disorders in Antibody Production and Related Primary Immunodeficiency States". This study investigates gene abnormalities in Primary Immune Deficiency(PID) with a goal of improving the diagnosis and treatment of patients. The specific disorders include: 1. X linked hyper IgM Syndrome which is caused by an abnormality in the CD40L gene. 2. NEMO associated immune deficiency wh...
What is the current status of trial NCT00266513?
This trial is currently terminated. The enrollment target is 119 participants. The study started on 2005-12-14. Estimated completion is 2013-07-11.
Who is sponsoring clinical trial NCT00266513?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
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