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NCT00242723 · ClinicalTrials.gov registry record

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

A clinical trial of Thoracic Cancers and Malignant Pleural Mesotheliomas NOS, sponsored by National Cancer Institute (NCI).

Recruiting
Registry status
1,310
Enrollment target
1
Study location

NCT00242723 is a study of Thoracic Cancers and Malignant Pleural Mesotheliomas NOS that is actively recruiting participants, run by National Cancer Institute (NCI). The registered enrollment target is 1,310 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT00242723, a study of Thoracic Cancers and Malignant Pleural Mesotheliomas NOS, is actively recruiting participants, sponsored by National Cancer Institute (NCI).

RECRUITING
Registry status
1,310 participants
Enrollment target
1
Study location

Study Summary

Background: * Chromatin is is the structural building block of a chromosome. It is found inside the nucleus of the cell and consists of a complex of DNA and protein. * Cancers of the lung, pleura (lung lining) and esophagus show profound changes in chromatin structure that may affect the course of disease in patients. * A better understanding of these diseases and the genetic changes associated with them may be helpful in developing new treatments for them. Objectives: * To evaluate people with cancer of the lung, pleura or esophagus for participation in NCI clinical trials. * To obtain biopsies (small pieces of tissue) from tumor, normal tissue and blood samples to learn more about the cellular changes in blood and tissue in tumors of the lung, esophagus and pleura and surrounding structures in the chest. Eligibility: Patients 2 years of age and older with cancer of the lung, esophagus, pleura, mediastinum or chest wall, or cancers of other origin that have invaded the lung. Note: Patients \>= 2 years of age and under 18 years of age may only participate in research sample collection. Design: * Up to 1310 patients may be included in this study. * Patients undergo standard tests for evaluating the stage of their disease and for determining eligibility for an NCI investigational treatment study. * All patients undergo bronchoscopy and bronchoalveolar lavage ("washing" with salt water) to assess their tumor and collect a sample of normal tissue. Patients whose tumor is located on the outside portion of the lung may also undergo thoracoscopy to obtain a tumor sample. For bronchoscopy and bronchoalveolar lavage a tube with a light is passed through the nose or mouth into the lungs to examine the airways. Salt water is injected through the tube and then withdrawn to obtain cells for laboratory studies. For the thoracoscopy a small tube with a light is put through a small hole in the chest to obtain the tumor sample. Both procedures are usually done under general an

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 1,310 participants
Start Date 2005-11-09

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00242723

The ClinicalTrials.gov registry entry for NCT00242723 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,310 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Thoracic Cancers appearing as the primary indexed condition, and to 0 interventions.

NCT00242723 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00242723 about?

NCT00242723 is a clinical study titled "Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining". Background: * Chromatin is is the structural building block of a chromosome. It is found inside the nucleus of the cell and consists of a complex of DNA and protein. * Cancers of the lung, pleura (lung lining) and esophagus show profound changes in chromatin structure that may affect the course of ...

What is the current status of trial NCT00242723?

This trial is currently recruiting. The enrollment target is 1,310 participants. The study started on 2005-11-09.

What conditions does trial NCT00242723 study?

This clinical trial studies the following conditions: Thoracic Cancers, Malignant Pleural Mesotheliomas NOS, Esophageal Cancers NOS, Lung Cancer NOS, Cancers of Non Thoracic Origin With Metastases to the Lungs or Pleura.

Who is sponsoring clinical trial NCT00242723?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00242723 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.