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NCT00238277 · ClinicalTrials.gov registry record · Phase 2

Temozolomide During and After Radiation Therapy in Treating Patients Who Have Undergone Previous Surgery and Placement of Gliadel Wafers for Newly Diagnosed Glioblastoma Multiforme

A Phase 2 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Terminated
Registry status
Phase 2
Development phase
15
Enrollment target

NCT00238277 is a Phase 2 study that was terminated before completion, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 15 participants.

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The verdict

NCT00238277, a Phase 2 study, was terminated before completion, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

TERMINATED
Registry status
Phase 2
Development phase
15 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving temozolomide during and after radiation therapy may kill any tumor cells that remain after surgery and placement of Gliadel wafers. PURPOSE: This phase II trial is studying how well giving temozolomide during and after radiation therapy works in treating patients who have undergone previous surgery and placement of Gliadel wafers for newly diagnosed glioblastoma multiforme.

Interventions

  • DRUG temozolomide
  • PROCEDURE adjuvant therapy
  • PROCEDURE radiation therapy
  • PROCEDURE chemotherapy

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2005-02-15
Est. Completion 2007-12-11
Phase Phase 2

What the Registry Record Tells You About NCT00238277

The ClinicalTrials.gov registry entry for NCT00238277 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which temozolomide is the first listed.

NCT00238277 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00238277 about?

NCT00238277 is a clinical study titled "Temozolomide During and After Radiation Therapy in Treating Patients Who Have Undergone Previous Surgery and Placement of Gliadel Wafers for Newly Diagnosed Glioblastoma Multiforme". RATIONALE: Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving temozolomide during and after radiation therapy ...

What is the current status of trial NCT00238277?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2005-02-15. Estimated completion is 2007-12-11.

What interventions are being tested in trial NCT00238277?

The interventions under investigation include: temozolomide (DRUG), adjuvant therapy (PROCEDURE), radiation therapy (PROCEDURE), chemotherapy (PROCEDURE).

Who is sponsoring clinical trial NCT00238277?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.