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NCT00234702 · ClinicalTrials.gov registry record · Phase 2

Efficacy and Safety of Lanthanum Carbonate in Reducing Serum Phosphorus Levels in Subjects With Stage 3 and 4 Chronic Kidney Disease

A Phase 2 study of Kidney Diseases, sponsored by Shire.

Completed
Registry status
Phase 2
Development phase
84
Enrollment target
10
Study locations

NCT00234702: Completed Phase 2 study of Kidney Diseases, sponsored by Shire.

NCT00234702 is a Phase 2 study of Kidney Diseases that has completed, run by Shire. The registered enrollment target is 84 participants, below the 1,783-participant average among 38 other Kidney Diseases trials with a reported enrollment target (95% lower). The trial reports 10 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00234702, a Phase 2 study of Kidney Diseases, has completed, sponsored by Shire.

COMPLETED
Registry status
Phase 2
Development phase
84 participants
Enrollment target
10
Study locations

Study Summary

Chronic kidney disease (CKD) can result in a loss of ability to filter and excrete phosphate. The body's attempt to adjust to an increased level of phosphate in the blood can result in elevated levels of hormones and minerals resulting in serious clinical consequences. This study is being conducted to evaluate the safety and efficacy of lanthanum carbonate in lowering high levels of phosphorus in the blood in subjects with CKD Stages 3 and 4 compared to placebo.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Lanthanum carbonate

Study Locations (10)

California

  • VA Greater Los Angeles Health Care System - Los Angeles
  • Barnett Research & Communications Medical Corporation - Torrance

Colorado

  • Western Nephrology & Metabolic Bone Disease, PC - Thornton

Florida

  • Outcomes Research International, Inc. - Hudson

Minnesota

  • Twin Cities Clinical Research - Brooklyn Center

Missouri

  • St. Louis University/Nephrology - St Louis

North Carolina

  • University of North Carolina - Chapel Hill

Oregon

  • Northwest Renal Clinic - Portland

Tennessee

  • Nephrology Associates - Nashville

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2006-01-11
Est. Completion 2007-06-01
Phase Phase 2
Shire

245 total trials

What the finished NCT00234702 record still lists

NCT00234702 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 1,783-participant average among 38 other Kidney Diseases trials with a reported enrollment target (95% lower).

The record links to 1 condition, with Kidney Diseases appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00234702 lists 10 locations in 9 states (California, Colorado, Florida).

Frequently Asked Questions

What is clinical trial NCT00234702 about?

NCT00234702 is a clinical study titled "Efficacy and Safety of Lanthanum Carbonate in Reducing Serum Phosphorus Levels in Subjects With Stage 3 and 4 Chronic Kidney Disease". Chronic kidney disease (CKD) can result in a loss of ability to filter and excrete phosphate. The body's attempt to adjust to an increased level of phosphate in the blood can result in elevated levels of hormones and minerals resulting in serious clinical consequences. This study is being conducted ...

What is the current status of trial NCT00234702?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 84 participants. The study started on 2006-01-11. Estimated completion is 2007-06-01.

What conditions does trial NCT00234702 study?

This clinical trial studies the following conditions: Kidney Diseases.

What interventions are being tested in trial NCT00234702?

The interventions under investigation include: Placebo (DRUG), Lanthanum carbonate (DRUG).

Who is sponsoring clinical trial NCT00234702?

This trial is sponsored by Shire, which has 245 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00234702 being conducted?

This trial has 10 study locations across California, Colorado, Florida, Minnesota, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Kidney Diseases

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00234702's enrollment target sits among peer trials

84 24th of 38 higher than 15 of 38 other Kidney Diseases trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Kidney Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00234702, the US trial registry maintained by the National Library of Medicine. NCT00234702 (small enrollment · multi site footprint · completed) retrieved and formatted by PlainTrial, see methodology.