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COMPLETED Phase 2

Efficacy and Safety of Lanthanum Carbonate in Reducing Serum Phosphorus Levels in Subjects With Stage 3 and 4 Chronic Kidney Disease

NCT00234702 · View on ClinicalTrials.gov ↗

Study Summary

Chronic kidney disease (CKD) can result in a loss of ability to filter and excrete phosphate. The body's attempt to adjust to an increased level of phosphate in the blood can result in elevated levels of hormones and minerals resulting in serious clinical consequences. This study is being conducted to evaluate the safety and efficacy of lanthanum carbonate in lowering high levels of phosphorus in the blood in subjects with CKD Stages 3 and 4 compared to placebo.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Lanthanum carbonate

Study Locations (10)

California

  • VA Greater Los Angeles Health Care System — Los Angeles
  • Barnett Research & Communications Medical Corporation — Torrance

Colorado

  • Western Nephrology & Metabolic Bone Disease, PC — Thornton

Florida

  • Outcomes Research International, Inc. — Hudson

Minnesota

  • Twin Cities Clinical Research — Brooklyn Center

Missouri

  • St. Louis University/Nephrology — St Louis

North Carolina

  • University of North Carolina — Chapel Hill

Oregon

  • Northwest Renal Clinic — Portland

Tennessee

  • Nephrology Associates — Nashville

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2006-01-11
Est. Completion 2007-06-01
Phase Phase 2

Sponsor

Shire

56 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00234702

The ClinicalTrials.gov registry entry for NCT00234702 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 84 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shire, which has 56 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Kidney Diseases appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00234702 reports 10 study locations spanning 9 distinct geographic areas — top geographies include California, Colorado, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00234702 about?

NCT00234702 is a clinical study titled "Efficacy and Safety of Lanthanum Carbonate in Reducing Serum Phosphorus Levels in Subjects With Stage 3 and 4 Chronic Kidney Disease". Chronic kidney disease (CKD) can result in a loss of ability to filter and excrete phosphate. The body's attempt to adjust to an increased level of phosphate in the blood can result in elevated levels of hormones and minerals resulting in serious clinical consequences. This study is being conducted ...

What is the current status of trial NCT00234702?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 84 participants. The study started on 2006-01-11. Estimated completion is 2007-06-01.

What conditions does trial NCT00234702 study?

This clinical trial studies the following conditions: Kidney Diseases. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00234702?

The interventions under investigation include: Placebo (DRUG), Lanthanum carbonate (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00234702?

This trial is sponsored by Shire, which has 56 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00234702 being conducted?

This trial has 10 study locations across California, Colorado, Florida, Minnesota, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial