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NCT00200850 · ClinicalTrials.gov registry record · NA

Immunotherapy Administered Under the Tongue to Treat Dust Mite Allergy

A NA study, sponsored by University of Wisconsin, Madison.

Completed
Registry status
NA
Development phase
31
Enrollment target

NCT00200850: Completed NA study, sponsored by University of Wisconsin, Madison.

NCT00200850 is a NA study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 31 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00200850, a NA study, has completed, sponsored by University of Wisconsin, Madison.

COMPLETED
Registry status
NA
Development phase
31 participants
Enrollment target

Study Summary

This study will investigate sublingual immunotherapy (SLIT), a treatment involving antigens placement under the tongue to help asthma sufferers build a tolerance to the allergy-causing substances. Specifically, this study will determine the effectiveness of SLIT at two different dosing regimens for patients with intermittent mild asthma caused by dust mites.

Primary Outcome

Antigen challenge was performed using the antigen house dust mite. Increasing doses of antigen were inhaled and then lung function (using the procedure Spirometry, measuring Forced Expiatory Volume in the 1st second FEV1) was measured after each dose. The challenge was stopped once the lung function (FEV1) was dropped by 20% of percent predicted. The dose of antigen that caused a 20% drop in lung function is considered the bronchial threshold. The higher the dose of antigen that causes the drop

Interventions

  • BIOLOGICAL House Dust Mite SLIT
  • BIOLOGICAL High dose SLIT
  • BIOLOGICAL Placebo SLIT

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2006-01
Est. Completion 2008-10
Phase NA
University of Wisconsin, Madison

1,039 total trials

What the finished NCT00200850 record still lists

NCT00200850 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 3 interventions - of which House Dust Mite SLIT is the first listed.

NCT00200850 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00200850 about?

NCT00200850 is a clinical study titled "Immunotherapy Administered Under the Tongue to Treat Dust Mite Allergy". This study will investigate sublingual immunotherapy (SLIT), a treatment involving antigens placement under the tongue to help asthma sufferers build a tolerance to the allergy-causing substances. Specifically, this study will determine the effectiveness of SLIT at two different dosing regimens for ...

What is the current status of trial NCT00200850?

This trial is currently completed. It is a NA study. The enrollment target is 31 participants. The study started on 2006-01. Estimated completion is 2008-10.

What interventions are being tested in trial NCT00200850?

The interventions under investigation include: House Dust Mite SLIT (BIOLOGICAL), High dose SLIT (BIOLOGICAL), Placebo SLIT (BIOLOGICAL).

Who is sponsoring clinical trial NCT00200850?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00200850's enrollment target sits among peer trials

31 1592nd of 2000 higher than 408 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00200850, the US trial registry maintained by the National Library of Medicine. NCT00200850 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.