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NCT00172081 · ClinicalTrials.gov registry record · Phase 3

TOP: Recombinant Human Parathyroid Hormone (ALX1-11) on Fracture Incidence in Women With Postmenopausal Osteoporosis

A Phase 3 study, sponsored by Shire.

Completed
Registry status
Phase 3
Development phase
2,532
Enrollment target

NCT00172081 is a Phase 3 study that has completed, run by Shire. The registered enrollment target is 2,532 participants.

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The verdict

NCT00172081, a Phase 3 study, has completed, sponsored by Shire.

COMPLETED
Registry status
Phase 3
Development phase
2,532 participants
Enrollment target

Study Summary

This is an 18-month, double-blind, placebo-controlled, Phase III trial with a 12-month interim analysis of the effect of ALX1-11, recombinant human parathyroid hormone (1-84) (rhPTH \[1-84\]), on fracture incidence in women with postmenopausal osteoporosis, the TOP study.

Interventions

  • DRUG placebo
  • DRUG ALX1-11

Trial Details

FieldValue
Enrollment Target 2,532 participants
Start Date 2000-04-27
Est. Completion 2003-11-07
Phase Phase 3

Sponsor

Shire

245 total trials

What the Registry Record Tells You About NCT00172081

The ClinicalTrials.gov registry entry for NCT00172081 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 2,532 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shire, which has 245 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT00172081 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00172081 about?

NCT00172081 is a clinical study titled "TOP: Recombinant Human Parathyroid Hormone (ALX1-11) on Fracture Incidence in Women With Postmenopausal Osteoporosis". This is an 18-month, double-blind, placebo-controlled, Phase III trial with a 12-month interim analysis of the effect of ALX1-11, recombinant human parathyroid hormone (1-84) (rhPTH \[1-84\]), on fracture incidence in women with postmenopausal osteoporosis, the TOP study.

What is the current status of trial NCT00172081?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 2,532 participants. The study started on 2000-04-27. Estimated completion is 2003-11-07.

What interventions are being tested in trial NCT00172081?

The interventions under investigation include: placebo (DRUG), ALX1-11 (DRUG).

Who is sponsoring clinical trial NCT00172081?

This trial is sponsored by Shire, which has 245 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.