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NCT00136786 · ClinicalTrials.gov registry record · Phase 1
Effect of Memantine Versus Bupropion on Smoking Relapse in Nicotine-Dependent Individuals - 3
A Phase 1 study of Tobacco Use Disorder, sponsored by New York State Psychiatric Institute.
- Completed
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT00136786: Completed Phase 1 study of Tobacco Use Disorder, sponsored by New York State Psychiatric Institute.
NCT00136786 is a Phase 1 study of Tobacco Use Disorder that has completed, run by New York State Psychiatric Institute. The registered enrollment target is 25 participants, below the 239-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00136786, a Phase 1 study of Tobacco Use Disorder, has completed, sponsored by New York State Psychiatric Institute.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
One of nicotine's effects on the body is at the level of the NMDA receptors in the brain. Memantine is a drug that also affects NMDA receptors, making it a candidate for the treatment of nicotine addiction. The purpose of this study is to evaluate the effectiveness of memantine using a laboratory model of smoking relapse in nicotine dependent volunteers. Investigators will compare the effects of memantine with bupropion, medication currently used to facilitate smoking cessation.
Conditions Studied
Interventions
- DRUG Memantine
Study Locations (1)
New York
- New York State Psychiatric Institute - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2006-12 |
| Est. Completion | 2009-05 |
| Phase | Phase 1 |
What the finished NCT00136786 record still lists
NCT00136786 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 239-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Tobacco Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which Memantine is the first listed.
NCT00136786 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT00136786 about?
NCT00136786 is a clinical study titled "Effect of Memantine Versus Bupropion on Smoking Relapse in Nicotine-Dependent Individuals - 3". One of nicotine's effects on the body is at the level of the NMDA receptors in the brain. Memantine is a drug that also affects NMDA receptors, making it a candidate for the treatment of nicotine addiction. The purpose of this study is to evaluate the effectiveness of memantine using a laboratory mo...
What is the current status of trial NCT00136786?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2006-12. Estimated completion is 2009-05.
What conditions does trial NCT00136786 study?
This clinical trial studies the following conditions: Tobacco Use Disorder.
What interventions are being tested in trial NCT00136786?
The interventions under investigation include: Memantine (DRUG).
Who is sponsoring clinical trial NCT00136786?
This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00136786 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tobacco Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00136786's enrollment target sits among peer trials
25 65th of 70 higher than 6 of 70 other Tobacco Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tobacco Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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