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NCT00133224 · ClinicalTrials.gov registry record · Phase 3

Docetaxel in Combination With GVAX ® Immunotherapy Versus Docetaxel and Prednisone in Prostate Cancer Patients

A Phase 3 study, sponsored by Cell Genesys.

Terminated
Registry status
Phase 3
Development phase
408
Enrollment target

NCT00133224: Clinical Trial Phase 3 study, sponsored by Cell Genesys.

NCT00133224 is a Phase 3 study that was terminated before completion, run by Cell Genesys. The registered enrollment target is 408 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00133224, a Phase 3 study, was terminated before completion, sponsored by Cell Genesys.

TERMINATED
Registry status
Phase 3
Development phase
408 participants
Enrollment target

Study Summary

The primary objective of this study is to compare the duration of survival between patients receiving docetaxel in combination with the GVAX® vaccine for prostate cancer versus patients receiving docetaxel and prednisone treatment in patients with prostate cancer who no longer respond to hormone therapy, who have documented metastases with pain. Patients may have had up to one prior non-taxane chemotherapy treatment.

Interventions

  • BIOLOGICAL Immunotherapy allogeneic GM-CSF secreting cellular vaccine
  • DRUG Chemotherapy (docetaxel and prednisone)

Trial Details

FieldValue
Enrollment Target 408 participants
Start Date 2005-07
Est. Completion 2009-06
Phase Phase 3
Cell Genesys

7 total trials

Why NCT00133224 stopped before completion

NCT00133224 is an interventional study that assigns participants to a tested intervention. The registered 408 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (47% lower).

The record links to 0 conditions, and to 2 interventions - of which Immunotherapy allogeneic GM-CSF secreting cellular vaccine is the first listed.

NCT00133224 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00133224 about?

NCT00133224 is a clinical study titled "Docetaxel in Combination With GVAX ® Immunotherapy Versus Docetaxel and Prednisone in Prostate Cancer Patients". The primary objective of this study is to compare the duration of survival between patients receiving docetaxel in combination with the GVAX® vaccine for prostate cancer versus patients receiving docetaxel and prednisone treatment in patients with prostate cancer who no longer respond to hormone the...

What is the current status of trial NCT00133224?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 408 participants. The study started on 2005-07. Estimated completion is 2009-06.

What interventions are being tested in trial NCT00133224?

The interventions under investigation include: Immunotherapy allogeneic GM-CSF secreting cellular vaccine (BIOLOGICAL), Chemotherapy (docetaxel and prednisone) (DRUG).

Who is sponsoring clinical trial NCT00133224?

This trial is sponsored by Cell Genesys, which has 7 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00133224's enrollment target sits among peer trials

408 911th of 2000 higher than 1,088 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00133224, the US trial registry maintained by the National Library of Medicine. NCT00133224 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.