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NCT00127036 · ClinicalTrials.gov registry record · Phase 2
Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A)
A Phase 2 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
- Terminated
- Registry status
- Phase 2
- Development phase
- 65
- Enrollment target
NCT00127036: Clinical Trial Phase 2 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
NCT00127036 is a Phase 2 study that was terminated before completion, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 65 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (51% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00127036, a Phase 2 study, was terminated before completion, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 65 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if the investigators can predict the sensitivity or resistance of colon cancer to the two available first line chemotherapy agents.
Primary Outcome
Investigators would develop tumor tissue classifiers to predict response to the XELOX arm or XELIRI arm; with gene expression profiles on 75 patients on each of 2 arms, construct 2 classifiers to distinguish responders (complete responses, partial responses, stable disease) from non-responders (progressive disease).
Interventions
- DRUG Bevacizumab
- DRUG XELOX
- DRUG XELIRI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2003-10 |
| Est. Completion | 2010-12 |
| Phase | Phase 2 |
Why NCT00127036 stopped before completion
NCT00127036 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (51% lower).
The record links to 0 conditions, and to 3 interventions - of which Bevacizumab is the first listed.
NCT00127036 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00127036 about?
NCT00127036 is a clinical study titled "Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A)". The purpose of this study is to determine if the investigators can predict the sensitivity or resistance of colon cancer to the two available first line chemotherapy agents.
What is the current status of trial NCT00127036?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 65 participants. The study started on 2003-10. Estimated completion is 2010-12.
What interventions are being tested in trial NCT00127036?
The interventions under investigation include: Bevacizumab (DRUG), XELOX (DRUG), XELIRI (DRUG).
Who is sponsoring clinical trial NCT00127036?
This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00127036's enrollment target sits among peer trials
65 987th of 2000 higher than 1,005 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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