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NCT00122278 · ClinicalTrials.gov registry record · Phase 3
Headache in the Emergency Department (ED) - A Multi-Center Research Network to Optimize the ED Treatment of Migraines
A Phase 3 study, sponsored by Montefiore Medical Center.
- Completed
- Registry status
- Phase 3
- Development phase
- 205
- Enrollment target
NCT00122278: Completed Phase 3 study, sponsored by Montefiore Medical Center.
NCT00122278 is a Phase 3 study that has completed, run by Montefiore Medical Center. The registered enrollment target is 205 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00122278, a Phase 3 study, has completed, sponsored by Montefiore Medical Center.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 205 participants
- Enrollment target
Study Summary
Migraines are a specific type of headache that frequently recur and are very painful. Although there are many medications that are effective against migraines, none of these medications cure 100% of migraines. Another problem with migraines is that although many times they get better after intravenous (IV) treatment in the emergency room (ER), about 1/3 of the time migraines recur the next day. The purpose of this research project is to see if adding a medication called dexamethasone to standard ER therapy will help patients get better quicker and stay pain-free more often than if they receive placebo.
Primary Outcome
Achieve headache freedom within two hours in the emergency department and no recurrence of pain within 24 hours of emergency department discharge
Interventions
- OTHER Placebo
- DRUG Dexamethasone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 205 participants |
| Start Date | 2005-07 |
| Est. Completion | 2006-08 |
| Phase | Phase 3 |
What the finished NCT00122278 record still lists
NCT00122278 is an interventional study that assigns participants to a tested intervention. The registered 205 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00122278 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00122278 about?
NCT00122278 is a clinical study titled "Headache in the Emergency Department (ED) - A Multi-Center Research Network to Optimize the ED Treatment of Migraines". Migraines are a specific type of headache that frequently recur and are very painful. Although there are many medications that are effective against migraines, none of these medications cure 100% of migraines. Another problem with migraines is that although many times they get better after intraveno...
What is the current status of trial NCT00122278?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 205 participants. The study started on 2005-07. Estimated completion is 2006-08.
What interventions are being tested in trial NCT00122278?
The interventions under investigation include: Placebo (OTHER), Dexamethasone (DRUG).
Who is sponsoring clinical trial NCT00122278?
This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00122278's enrollment target sits among peer trials
205 1350th of 2000 higher than 649 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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