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NCT00112034 · ClinicalTrials.gov registry record · Phase 4
AVONEX® Combination Trial - "ACT"
A Phase 4 study, sponsored by Biogen.
- Completed
- Registry status
- Phase 4
- Development phase
- 350
- Enrollment target
NCT00112034: Completed Phase 4 study, sponsored by Biogen.
NCT00112034 is a Phase 4 study that has completed, run by Biogen. The registered enrollment target is 350 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00112034, a Phase 4 study, has completed, sponsored by Biogen.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 350 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the efficacy and safety of combination therapy with AVONEX plus low dose oral methotrexate (MTX), every other month courses of intravenous methylprednisolone (IVMP), or both in patients with continued disease activity on AVONEX monotherapy.
Interventions
- DRUG Methotrexate
- DRUG IV methylprednisolone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 350 participants |
| Start Date | 2003-06 |
| Est. Completion | 2007-05 |
| Phase | Phase 4 |
What the finished NCT00112034 record still lists
NCT00112034 is an interventional study that assigns participants to a tested intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (32% lower).
The record links to 0 conditions, and to 2 interventions - of which Methotrexate is the first listed.
NCT00112034 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00112034 about?
NCT00112034 is a clinical study titled "AVONEX® Combination Trial - "ACT"". The purpose of this study is to determine the efficacy and safety of combination therapy with AVONEX plus low dose oral methotrexate (MTX), every other month courses of intravenous methylprednisolone (IVMP), or both in patients with continued disease activity on AVONEX monotherapy.
What is the current status of trial NCT00112034?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 350 participants. The study started on 2003-06. Estimated completion is 2007-05.
What interventions are being tested in trial NCT00112034?
The interventions under investigation include: Methotrexate (DRUG), IV methylprednisolone (DRUG).
Who is sponsoring clinical trial NCT00112034?
This trial is sponsored by Biogen, which has 334 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00112034's enrollment target sits among peer trials
350 231st of 2000 higher than 1,761 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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