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NCT00076466 · ClinicalTrials.gov registry record
Brain Changes Associated With Learning a Motor Task
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 72
- Enrollment target
NCT00076466: Completed study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00076466 is a clinical trial that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 72 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00076466 has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 72 participants
- Enrollment target
Study Summary
This study will determine: 1) whether learning a task with the dominant hand is accompanied by changes in the area of the brain that controls hand movement, and 2) how the brain is able to make these changes. Previous studies have shown that practicing a motor task can change brain excitability, but it is not known how well brain excitabilities are changed during motor learning. This study will measure changes in activity of the part of the brain that controls hand movement before, during, and after exercising the hand on a response pad. Healthy normal volunteers between 18 and 40 years of age may be eligible for this study. Candidates who have not been evaluated at NIH within the past year will be screened with a brief interview about their current state of health and clinical and neurological examinations. Participants will undergo the following procedures: Learning a finger movement/reaction time task For this procedure, participants sit in front of a computer monitor with the index, middle, ring, and little fingers placed flat on four corresponding buttons of a response pad. They are asked to press one of the four buttons as fast as they can in response to an asterisk displayed on the monitor. The position of the asterisk indicates which button to push. Subjects perform nine sets of 120-button pushes with a 15-minute rest between each set. During the rest period, subjects undergo transcranial magnetic stimulation (described below), which causes twitches in the hand muscles. The electrical activity corresponding to the twitches is recorded by attaching electrodes (small metal disks) to the skin over the hand muscles. Transcranial magnetic stimulation For this test, an insulated wire coil is held over the scalp. A brief electrical current passes through the coil, creating a magnetic pulse that electrically stimulates the brain. The subject hears a click and may feel a pulling sensation on the scalp under the coil. The stimulation may also cause twitching in t
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2004-01-22 |
| Est. Completion | 2009-01-14 |
What the finished NCT00076466 record still lists
NCT00076466 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 72 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00076466 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00076466 about?
NCT00076466 is a clinical study titled "Brain Changes Associated With Learning a Motor Task". This study will determine: 1) whether learning a task with the dominant hand is accompanied by changes in the area of the brain that controls hand movement, and 2) how the brain is able to make these changes. Previous studies have shown that practicing a motor task can change brain excitability, but...
What is the current status of trial NCT00076466?
This trial is currently completed. The enrollment target is 72 participants. The study started on 2004-01-22. Estimated completion is 2009-01-14.
Who is sponsoring clinical trial NCT00076466?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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