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NCT00066742 · ClinicalTrials.gov registry record · Phase 2
Tirapazamine Combined With Chemo and RT in Limited-Stage Small Cell Lung Cancer
A Phase 2 study of Limited Stage Small Cell Lung Cancer, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 2
- Development phase
- 72
- Enrollment target
- 1
- Study location
NCT00066742: Completed Phase 2 study of Limited Stage Small Cell Lung Cancer, sponsored by National Cancer Institute (NCI).
NCT00066742 is a Phase 2 study of Limited Stage Small Cell Lung Cancer that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 72 participants, below the 301-participant average among 4 other Limited Stage Small Cell Lung Cancer trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00066742, a Phase 2 study of Limited Stage Small Cell Lung Cancer, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 72 participants
- Enrollment target
- 1
- Study location
Study Summary
This phase II trial is studying how well giving tirapazamine together with cisplatin, etoposide, and radiation therapy works in treating patients with limited-stage small cell lung cancer. Drugs used in chemotherapy, such as cisplatin and etoposide, work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Tirapazamine may make the tumor cells more sensitive to chemotherapy and radiation therapy. Combining chemotherapy and radiation therapy with tirapazamine may kill more tumor cells.
Primary Outcome
Overall survival was defined as the time from date of enrollment until the date of death due to any cause. Patients last known to be alive were censored at the date of last conatct. Patients were followed for a maximum of 3 years from the date of enrollment.
Conditions Studied
Interventions
- OTHER laboratory biomarker analysis
- DRUG cisplatin
- DRUG etoposide
- RADIATION radiation therapy
- DRUG tirapazamine
Study Locations (1)
Texas
- Southwest Oncology Group (SWOG) Research Base - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2003-09 |
| Est. Completion | 2009-08 |
| Phase | Phase 2 |
What the finished NCT00066742 record still lists
NCT00066742 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 301-participant average among 4 other Limited Stage Small Cell Lung Cancer trials with a reported enrollment target (76% lower).
The record links to 1 condition, with Limited Stage Small Cell Lung Cancer appearing as the primary indexed condition, and to 5 interventions - of which laboratory biomarker analysis is the first listed.
NCT00066742 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT00066742 about?
NCT00066742 is a clinical study titled "Tirapazamine Combined With Chemo and RT in Limited-Stage Small Cell Lung Cancer". This phase II trial is studying how well giving tirapazamine together with cisplatin, etoposide, and radiation therapy works in treating patients with limited-stage small cell lung cancer. Drugs used in chemotherapy, such as cisplatin and etoposide, work in different ways to stop tumor cells from di...
What is the current status of trial NCT00066742?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 72 participants. The study started on 2003-09. Estimated completion is 2009-08.
What conditions does trial NCT00066742 study?
This clinical trial studies the following conditions: Limited Stage Small Cell Lung Cancer.
What interventions are being tested in trial NCT00066742?
The interventions under investigation include: laboratory biomarker analysis (OTHER), cisplatin (DRUG), etoposide (DRUG), radiation therapy (RADIATION), tirapazamine (DRUG).
Who is sponsoring clinical trial NCT00066742?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00066742 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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