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NCT00058370 · ClinicalTrials.gov registry record · NA

Intrathecal Radioimmunotherapy, Radiation Therapy, and Chemotherapy After Surgery in Treating Patients With Medulloblastoma

A NA study of Brain and Central Nervous System Tumors, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
NA
Development phase
6
Enrollment target
2
Study locations

NCT00058370 is a NA study of Brain and Central Nervous System Tumors that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 6 participants, below the 183-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT00058370, a NA study of Brain and Central Nervous System Tumors, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
NA
Development phase
6 participants
Enrollment target
2
Study locations

Study Summary

RATIONALE: Radioimmunotherapy uses radiolabeled monoclonal antibodies to locate tumor cells and deliver radioactive tumor-killing substances to them without harming normal cells. Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining intrathecal radioimmunotherapy and radiation therapy with combination chemotherapy may kill any tumor cells remaining after surgery. PURPOSE: Phase II trial to study the effectiveness of combining intrathecal radioimmunotherapy and radiation therapy with combination chemotherapy in treating patients who have undergone surgery for medulloblastoma.

Interventions

  • DRUG cisplatin
  • PROCEDURE adjuvant therapy
  • DRUG vincristine sulfate
  • DRUG lomustine
  • RADIATION iodine I 131 monoclonal antibody 3F8

Study Locations (2)

New York

  • Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center - New York
  • Memorial Sloan-Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2003-02
Est. Completion 2019-06
Phase NA

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT00058370

The ClinicalTrials.gov registry entry for NCT00058370 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 183-participant average among 45 other Brain and Central Nervous System Tumors trials with a reported enrollment target (97% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Brain and Central Nervous System Tumors appearing as the primary indexed condition, and to 5 interventions - of which cisplatin is the first listed.

NCT00058370 reports 2 study locations spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT00058370 about?

NCT00058370 is a clinical study titled "Intrathecal Radioimmunotherapy, Radiation Therapy, and Chemotherapy After Surgery in Treating Patients With Medulloblastoma". RATIONALE: Radioimmunotherapy uses radiolabeled monoclonal antibodies to locate tumor cells and deliver radioactive tumor-killing substances to them without harming normal cells. Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tu...

What is the current status of trial NCT00058370?

This trial is currently completed. It is a NA study. The enrollment target is 6 participants. The study started on 2003-02. Estimated completion is 2019-06.

What conditions does trial NCT00058370 study?

This clinical trial studies the following conditions: Brain and Central Nervous System Tumors.

What interventions are being tested in trial NCT00058370?

The interventions under investigation include: cisplatin (DRUG), adjuvant therapy (PROCEDURE), vincristine sulfate (DRUG), lomustine (DRUG), iodine I 131 monoclonal antibody 3F8 (RADIATION).

Who is sponsoring clinical trial NCT00058370?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00058370 being conducted?

This trial has 2 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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