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NCT00038857 · ClinicalTrials.gov registry record · Phase 2

Megadose CD34 Selected Progenitor Cells for Transplantation in Patients With Advanced Hematological Malignant Diseases

A Phase 2 study, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 2
Development phase
29
Enrollment target

NCT00038857: Completed Phase 2 study, sponsored by M.D. Anderson Cancer Center.

NCT00038857 is a Phase 2 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 29 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00038857, a Phase 2 study, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
29 participants
Enrollment target

Study Summary

Donor: This clinical study will evaluate the feasibility of a purified CD34 peripheral blood progenitor cell (PBPC) transplants in patients with hematological malignancies. The primary objectives of the study are to evaluate the recipient obtaining donor derived neutrophil engraftment and the incidence of acute graft versus host disease \[GvHD\] (grade III-IV). Secondary objectives include assessments of recipient having donor derived platelet engraftment, incidence of graft failure and chronic GvHD, overall and disease free survival, clinical safety and device performance of the CliniMACS CD34 selection device.

Interventions

  • DRUG Fludarabine
  • DRUG Melphalan
  • DRUG Thiotepa
  • DRUG Rabbit ATG
  • PROCEDURE Megadose of CD34 Selected Progenitor Cells

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2001-09
Est. Completion 2009-06
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT00038857

The ClinicalTrials.gov registry entry for NCT00038857 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Fludarabine is the first listed.

NCT00038857 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00038857 about?

NCT00038857 is a clinical study titled "Megadose CD34 Selected Progenitor Cells for Transplantation in Patients With Advanced Hematological Malignant Diseases". Donor: This clinical study will evaluate the feasibility of a purified CD34 peripheral blood progenitor cell (PBPC) transplants in patients with hematological malignancies. The primary objectives of the study are to evaluate the recipient obtaining donor derived neutrophil engraftment and the inci...

What is the current status of trial NCT00038857?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2001-09. Estimated completion is 2009-06.

What interventions are being tested in trial NCT00038857?

The interventions under investigation include: Fludarabine (DRUG), Melphalan (DRUG), Thiotepa (DRUG), Rabbit ATG (DRUG), Megadose of CD34 Selected Progenitor Cells (PROCEDURE).

Who is sponsoring clinical trial NCT00038857?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.