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NCT00027170 · ClinicalTrials.gov registry record
Technical Development of Cardiovascular Magnetic Resonance Imaging
A clinical trial, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Completed
- Registry status
- 8,781
- Enrollment target
NCT00027170: Completed study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
NCT00027170 is a clinical trial that has completed, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 8,781 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00027170 has completed, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- COMPLETED
- Registry status
- 8,781 participants
- Enrollment target
Study Summary
This study will explore new ways of using magnetic resonance imaging (MRI) to evaluate the heart and blood vessels of patients with cardiovascular disease, including better detection of myocardial infarction (heart attack) and blockage of heart and leg arteries. Patients 18 years of age and older with cardiovascular disease may be eligible for this study. All participants will have magnetic resonance imaging of the heart. MRI uses a magnetic field and radio waves to show structural and chemical changes in tissues. For the procedure, the patient lies on a table surrounded by a metal cylinder (the scanner). A 'gadolinium contrast' material may be injected into the patient s vein during part of the study to brighten the images. Patients wear earplugs during the scan to muffle loud knocking sounds caused by the electrical switching of the magnetic fields. They will be asked to hold their breath intermittently for 5 to 20 seconds during the scan. They will be monitored with an electrocardiogram (EKG) during the procedure and will be in contact by intercom at all times with the person performing the scan. Patients can request to stop the study and come out of the scanner at any time. The procedure may last from 30 to 90 minutes. An echocardiogram a test that uses sound waves to produce pictures of the heart and blood vessels-may be done to confirm the MRI findings. In addition, patients may undergo one or more of the following optional studies: * Dobutamine stress MRI - This test uses dobutamine-a medicine that simulates exercise by increasing heart rate and heart function-to detect blockages in the coronary arteries (vessels that supply oxygen and nutrients to the heart) and locate areas of the heart that are permanently damaged, perhaps by a previous heart attack. For this test, MRI pictures of the heart are taken before, during and after administration of dobutamine. Gadolinium may be injected during part of the study to brighten the images. An EKG will be used to m
Primary Outcome
examine the rate of major cardiovascular events (MACE) defined as cardiac death, non- fatal myocardial infarction, cerebrovascular / transient ischemic attack, and revascularization in patients undergoing stress or rest cardiac MRI and to relate these events to the extent of ischemia and infarction seen on the MRI exams
Interventions
- DEVICE Siemens MRI scanner
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8,781 participants |
| Start Date | 2001-11-26 |
| Est. Completion | 2020-11-19 |
What the finished NCT00027170 record still lists
NCT00027170 is an observational study that tracks outcomes without assigning an intervention. Its 8,781 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 1 intervention - of which Siemens MRI scanner is the first listed.
NCT00027170 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00027170 about?
NCT00027170 is a clinical study titled "Technical Development of Cardiovascular Magnetic Resonance Imaging". This study will explore new ways of using magnetic resonance imaging (MRI) to evaluate the heart and blood vessels of patients with cardiovascular disease, including better detection of myocardial infarction (heart attack) and blockage of heart and leg arteries. Patients 18 years of age and older w...
What is the current status of trial NCT00027170?
This trial is currently completed. The enrollment target is 8,781 participants. The study started on 2001-11-26. Estimated completion is 2020-11-19.
What interventions are being tested in trial NCT00027170?
The interventions under investigation include: Siemens MRI scanner (DEVICE).
Who is sponsoring clinical trial NCT00027170?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
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