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NCT00025233 · ClinicalTrials.gov registry record · Phase 2

Bevacizumab in Treating Patients With Persistent or Recurrent Cancer of the Cervix

A Phase 2 study of Cervical Squamous Cell Carcinoma and Recurrent Cervical Cancer, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
50
Enrollment target
1
Study location

NCT00025233: Completed Phase 2 study of Cervical Squamous Cell Carcinoma and Recurrent Cervical Cancer, sponsored by National Cancer Institute (NCI).

NCT00025233 is a Phase 2 study of Cervical Squamous Cell Carcinoma and Recurrent Cervical Cancer that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 50 participants, below the 119-participant average among 13 other Cervical Squamous Cell Carcinoma trials with a reported enrollment target (58% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00025233, a Phase 2 study of Cervical Squamous Cell Carcinoma and Recurrent Cervical Cancer, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

This phase II trial is to see if bevacizumab works in treating patients who have persistent or recurrent cancer of the cervix. Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or deliver cancer-killing substances to them.

Primary Outcome

Whether or not the patient survived progression-free for at least 6 months.

Interventions

  • OTHER laboratory biomarker analysis
  • BIOLOGICAL bevacizumab

Study Locations (1)

Pennsylvania

  • Gynecologic Oncology Group - Philadelphia

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2002-04
Est. Completion 2009-07
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00025233 record still lists

NCT00025233 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 119-participant average among 13 other Cervical Squamous Cell Carcinoma trials with a reported enrollment target (58% lower).

The record links to 2 conditions, with Cervical Squamous Cell Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which laboratory biomarker analysis is the first listed.

NCT00025233 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT00025233 about?

NCT00025233 is a clinical study titled "Bevacizumab in Treating Patients With Persistent or Recurrent Cancer of the Cervix". This phase II trial is to see if bevacizumab works in treating patients who have persistent or recurrent cancer of the cervix. Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells an...

What is the current status of trial NCT00025233?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2002-04. Estimated completion is 2009-07.

What conditions does trial NCT00025233 study?

This clinical trial studies the following conditions: Cervical Squamous Cell Carcinoma, Recurrent Cervical Cancer.

What interventions are being tested in trial NCT00025233?

The interventions under investigation include: laboratory biomarker analysis (OTHER), bevacizumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT00025233?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00025233 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cervical Squamous Cell Carcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00025233's enrollment target sits among peer trials

50 9th of 13 higher than 5 of 13 other Cervical Squamous Cell Carcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cervical Squamous Cell Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00025233, the US trial registry maintained by the National Library of Medicine. NCT00025233 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.