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NCT00017147 · ClinicalTrials.gov registry record · Phase 3
S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma
A Phase 3 study, sponsored by SWOG Cancer Research Network.
- Completed
- Registry status
- Phase 3
- Development phase
- 183
- Enrollment target
NCT00017147: Completed Phase 3 study, sponsored by SWOG Cancer Research Network.
NCT00017147 is a Phase 3 study that has completed, run by SWOG Cancer Research Network. The registered enrollment target is 183 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (76% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00017147, a Phase 3 study, has completed, sponsored by SWOG Cancer Research Network.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 183 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. O6-benzylguanine may help carmustine kill more tumor cells by making tumor cells more sensitive to the drug. It is not yet known whether radiation therapy and carmustine are more effective with or without O6-benzylguanine. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy plus carmustine with or without O6-benzylguanine in treating patients who have newly diagnosed glioblastoma multiforme or gliosarcoma.
Interventions
- RADIATION radiation therapy
- DRUG carmustine
- DRUG O6-Benzylguanine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 183 participants |
| Start Date | 2001-09 |
| Est. Completion | 2012-11 |
| Phase | Phase 3 |
What the finished NCT00017147 record still lists
NCT00017147 is an interventional study that assigns participants to a tested intervention. The registered 183 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (76% lower).
The record links to 0 conditions, and to 3 interventions - of which radiation therapy is the first listed.
NCT00017147 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00017147 about?
NCT00017147 is a clinical study titled "S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. O6-benzylguanine may help carmustine kill more tumor cells by making tumor cells more sensitive to the drug. It is ...
What is the current status of trial NCT00017147?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 183 participants. The study started on 2001-09. Estimated completion is 2012-11.
What interventions are being tested in trial NCT00017147?
The interventions under investigation include: radiation therapy (RADIATION), carmustine (DRUG), O6-Benzylguanine (DRUG).
Who is sponsoring clinical trial NCT00017147?
This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00017147's enrollment target sits among peer trials
183 1420th of 2000 higher than 580 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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