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NCT00006373 · ClinicalTrials.gov registry record · Phase 2

Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma

A Phase 2 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Completed
Registry status
Phase 2
Development phase
27
Enrollment target

NCT00006373: Completed Phase 2 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

NCT00006373 is a Phase 2 study that has completed, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 27 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00006373, a Phase 2 study, has completed, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

COMPLETED
Registry status
Phase 2
Development phase
27 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell or bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by autologous bone marrow transplantation or peripheral stem cell transplantation in treating patients who have non-Hodgkin's lymphoma or Hodgkin's lymphoma.

Primary Outcome

Progression-free survival as defined as the time from date of enrollment to the time of recurrence

Interventions

  • DRUG Mesna
  • DRUG etoposide
  • DRUG ifosfamide
  • DRUG topotecan hydrochloride
  • PROCEDURE autologous bone marrow transplantation

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2000-02
Est. Completion 2011-12
Phase Phase 2

What the finished NCT00006373 record still lists

NCT00006373 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower).

The record links to 0 conditions, and to 5 interventions - of which Mesna is the first listed.

NCT00006373 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00006373 about?

NCT00006373 is a clinical study titled "Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell or bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOS...

What is the current status of trial NCT00006373?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2000-02. Estimated completion is 2011-12.

What interventions are being tested in trial NCT00006373?

The interventions under investigation include: Mesna (DRUG), etoposide (DRUG), ifosfamide (DRUG), topotecan hydrochloride (DRUG), autologous bone marrow transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT00006373?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00006373's enrollment target sits among peer trials

27 1697th of 2000 higher than 293 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00006373, the US trial registry maintained by the National Library of Medicine. NCT00006373 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.