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NCT00005898 · ClinicalTrials.gov registry record · Phase 1
Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia
A Phase 1 study of Fanconi's Anemia, sponsored by University of Minnesota.
- Completed
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT00005898 is a Phase 1 study of Fanconi's Anemia that has completed, run by University of Minnesota. The registered enrollment target is 30 participants. The trial reports 1 study location across 1 state.
The verdict
NCT00005898, a Phase 1 study of Fanconi's Anemia, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
OBJECTIVES: I. Determine the probability of engraftment with total body irradiation, cyclophosphamide, fludarabine, and anti-thymocyte globulin followed by HLA nongenotypically identical donor, T-cell depleted hematopoietic cell transplantation in patients with Fanconi's anemia. II. Determine the incidence of acute and chronic graft-versus-host disease in these patients after undergoing this treatment regimen. III. Determine the one-year survival rate in these patients after undergoing this treatment regimen. IV. Determine the toxicity of this treatment regimen in these patients. V. Determine the incidence of relapse in patients with myelodysplastic syndrome or acute myeloid leukemia after undergoing this treatment regimen.
Conditions Studied
Interventions
- DRUG fludarabine
- DRUG cyclophosphamide
- DRUG filgrastim
- DRUG cyclosporine
- DRUG anti-thymocyte globulin
Study Locations (1)
Minnesota
- University of Minnesota Cancer Center - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2000-02 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00005898
The ClinicalTrials.gov registry entry for NCT00005898 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Fanconi's Anemia appearing as the primary indexed condition, and to 5 interventions - of which fludarabine is the first listed.
NCT00005898 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.
Frequently Asked Questions
What is clinical trial NCT00005898 about?
NCT00005898 is a clinical study titled "Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia". OBJECTIVES: I. Determine the probability of engraftment with total body irradiation, cyclophosphamide, fludarabine, and anti-thymocyte globulin followed by HLA nongenotypically identical donor, T-cell depleted hematopoietic cell transplantation in patients with Fanconi's anemia. II. Determine the i...
What is the current status of trial NCT00005898?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2000-02.
What conditions does trial NCT00005898 study?
This clinical trial studies the following conditions: Fanconi's Anemia.
What interventions are being tested in trial NCT00005898?
The interventions under investigation include: fludarabine (DRUG), cyclophosphamide (DRUG), filgrastim (DRUG), cyclosporine (DRUG), anti-thymocyte globulin (DRUG).
Who is sponsoring clinical trial NCT00005898?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00005898 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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