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NCT00003343 · ClinicalTrials.gov registry record · Phase 3
Chemotherapy in Treating Patients Who Have Metastatic Prostate Cancer
A Phase 3 study, sponsored by Pfizer.
- Completed
- Registry status
- Phase 3
- Development phase
- 525
- Enrollment target
NCT00003343: Completed Phase 3 study, sponsored by Pfizer.
NCT00003343 is a Phase 3 study that has completed, run by Pfizer. The registered enrollment target is 525 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00003343, a Phase 3 study, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 525 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether mitoxantrone and prednisone are more effective with or without prinomastat in treating patients with metastatic prostate cancer. PURPOSE: Randomized phase III trial to determine the effectiveness of mitoxantrone and prednisone with or without prinomastat in treating patients who have metastatic prostate cancer that has not responded to hormone therapy.
Interventions
- DRUG prednisone
- DRUG endocrine-modulating drug therapy
- DRUG mitoxantrone hydrochloride
- DRUG prinomastat
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 525 participants |
| Start Date | 1998-03 |
| Phase | Phase 3 |
What the finished NCT00003343 record still lists
NCT00003343 is an interventional study that assigns participants to a tested intervention. The registered 525 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (32% lower).
The record links to 0 conditions, and to 4 interventions - of which prednisone is the first listed.
NCT00003343 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00003343 about?
NCT00003343 is a clinical study titled "Chemotherapy in Treating Patients Who Have Metastatic Prostate Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether mitoxantrone and prednisone are more effective with or without prinomastat in treating patients with metastatic prostate cancer. PURPOSE: Randomized ph...
What is the current status of trial NCT00003343?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 525 participants. The study started on 1998-03.
What interventions are being tested in trial NCT00003343?
The interventions under investigation include: prednisone (DRUG), endocrine-modulating drug therapy (DRUG), mitoxantrone hydrochloride (DRUG), prinomastat (DRUG).
Who is sponsoring clinical trial NCT00003343?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00003343's enrollment target sits among peer trials
525 715th of 2000 higher than 1,285 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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