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NCT00003027 · ClinicalTrials.gov registry record · Phase 3

Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma

A Phase 3 study, sponsored by Eastern Cooperative Oncology Group.

Completed
Registry status
Phase 3
Development phase
482
Enrollment target

NCT00003027 is a Phase 3 study that has completed, run by Eastern Cooperative Oncology Group. The registered enrollment target is 482 participants.

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The verdict

NCT00003027, a Phase 3 study, has completed, sponsored by Eastern Cooperative Oncology Group.

COMPLETED
Registry status
Phase 3
Development phase
482 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells. Interferon alfa may interfere with the growth of tumor cells. It is not yet known whether combination chemotherapy plus interleukin-2 and interferon alfa is more effective than combination chemotherapy alone for metastatic melanoma. PURPOSE: Randomized phase III trial to compare combination chemotherapy with or without interleukin-2 and interferon alfa in treating patients who have metastatic melanoma that cannot be treated by surgery.

Interventions

  • DRUG cisplatin
  • DRUG dacarbazine
  • BIOLOGICAL aldesleukin
  • BIOLOGICAL filgrastim
  • BIOLOGICAL recombinant interferon alfa

Trial Details

FieldValue
Enrollment Target 482 participants
Start Date 1997-11-13
Phase Phase 3

Sponsor

Eastern Cooperative Oncology Group

141 total trials

What the Registry Record Tells You About NCT00003027

The ClinicalTrials.gov registry entry for NCT00003027 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 482 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eastern Cooperative Oncology Group, which has 141 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which cisplatin is the first listed.

NCT00003027 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00003027 about?

NCT00003027 is a clinical study titled "Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells. Interferon alfa may interfere with the growth of tumor cells. It is not yet known whether combinati...

What is the current status of trial NCT00003027?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 482 participants. The study started on 1997-11-13.

What interventions are being tested in trial NCT00003027?

The interventions under investigation include: cisplatin (DRUG), dacarbazine (DRUG), aldesleukin (BIOLOGICAL), filgrastim (BIOLOGICAL), recombinant interferon alfa (BIOLOGICAL).

Who is sponsoring clinical trial NCT00003027?

This trial is sponsored by Eastern Cooperative Oncology Group, which has 141 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.