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NCT00002600 · ClinicalTrials.gov registry record · Phase 1

Combination Chemotherapy, Bone Marrow Transplantation, and Peripheral Stem Cell Transplantation in Treating Patients With Ovarian Epithelial Cancer

A Phase 1 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
Phase 1
Development phase
23
Enrollment target

NCT00002600: Completed Phase 1 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

NCT00002600 is a Phase 1 study that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 23 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002600, a Phase 1 study, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
Phase 1
Development phase
23 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bone marrow transplantation and peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy and kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy with carboplatin and cyclophosphamide followed by bone marrow and peripheral stem cell transplantation in treating patients who have advanced ovarian epithelial cancer.

Interventions

  • DRUG carboplatin
  • DRUG cyclophosphamide
  • PROCEDURE peripheral blood stem cell transplantation
  • BIOLOGICAL filgrastim
  • PROCEDURE autologous bone marrow transplantation

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 1994-10-21
Est. Completion 2001-07-25
Phase Phase 1

What the finished NCT00002600 record still lists

NCT00002600 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 5 interventions - of which carboplatin is the first listed.

NCT00002600 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002600 about?

NCT00002600 is a clinical study titled "Combination Chemotherapy, Bone Marrow Transplantation, and Peripheral Stem Cell Transplantation in Treating Patients With Ovarian Epithelial Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bone marrow transplantation and peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy and kill more tumor cells. PURPOSE: Phase I trial to st...

What is the current status of trial NCT00002600?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 1994-10-21. Estimated completion is 2001-07-25.

What interventions are being tested in trial NCT00002600?

The interventions under investigation include: carboplatin (DRUG), cyclophosphamide (DRUG), peripheral blood stem cell transplantation (PROCEDURE), filgrastim (BIOLOGICAL), autologous bone marrow transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT00002600?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002600's enrollment target sits among peer trials

23 1596th of 2000 higher than 400 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00002600, the US trial registry maintained by the National Library of Medicine. NCT00002600 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.