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Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Cancer of the Uterus
NCT00002546 · View on ClinicalTrials.gov ↗
Study Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether radiation therapy is more effective than combination chemotherapy in treating patients with cancer of the uterus. PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared to combination chemotherapy in treating patients with cancer of the uterus.
Conditions Studied
Interventions
- DRUG cisplatin
- RADIATION radiation therapy
- DRUG ifosfamide
- PROCEDURE adjuvant therapy
Study Locations (20)
Illinois
- Rush University Medical Center — Chicago
- MBCCOP - University of Illinois at Chicago — Chicago
- University of Chicago Cancer Research Center — Chicago
- CCOP - Central Illinois — Decatur
- CCOP - Evanston — Evanston
- — Hinsdale
- CCOP - Carle Cancer Center — Urbana
Indiana
- Indiana University Cancer Center — Indianapolis
- CCOP - Northern Indiana CR Consortium — South Bend
- Saint Joseph Regional Medical Center — South Bend
California
- Women's Cancer Center - Los Gatos — Los Gatos
- Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center — Orange
Alabama
- University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham
Arizona
- CCOP - Western Regional, Arizona — Phoenix
Colorado
- University of Colorado Cancer Center at University of Colorado Health Sciences Center — Denver
Delaware
- CCOP - Christiana Care Health Services — Newark
District of Columbia
- Walter Reed Army Medical Center — Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 216 participants |
| Start Date | 1993-12 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00002546
The ClinicalTrials.gov registry entry for NCT00002546 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 216 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gynecologic Oncology Group, which has 61 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Sarcoma appearing as the primary indexed condition, and to 4 interventions — of which cisplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00002546 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Illinois, Indiana, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00002546 about?
NCT00002546 is a clinical study titled "Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Cancer of the Uterus". RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether radiation therapy is more effective than combination chemotherapy in treating patients ...
What is the current status of trial NCT00002546?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 216 participants. The study started on 1993-12.
What conditions does trial NCT00002546 study?
This clinical trial studies the following conditions: Sarcoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00002546?
The interventions under investigation include: cisplatin (DRUG), radiation therapy (RADIATION), ifosfamide (DRUG), adjuvant therapy (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00002546?
This trial is sponsored by Gynecologic Oncology Group, which has 61 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00002546 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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