Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00091351 · ClinicalTrials.gov registry record · Phase 3
Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis
A Phase 3 study of Sarcoma, sponsored by Alliance for Clinical Trials in Oncology.
- Completed
- Registry status
- Phase 3
- Development phase
- 370
- Enrollment target
- 20
- Study locations
NCT00091351: Completed Phase 3 study of Sarcoma, sponsored by Alliance for Clinical Trials in Oncology.
NCT00091351 is a Phase 3 study of Sarcoma that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 370 participants, below the 918-participant average among 122 other Sarcoma trials with a reported enrollment target (60% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00091351, a Phase 3 study of Sarcoma, has completed, sponsored by Alliance for Clinical Trials in Oncology.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 370 participants
- Enrollment target
- 20
- Study locations
Study Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation therapy before surgery may shrink the tumor so that it can be removed. It is not yet known whether surgery is more effective with or without radiation therapy. PURPOSE: This randomized phase III trial is studying surgery alone to see how well it works compared to radiation therapy together with surgery in treating patients with primary soft tissue sarcoma of the retroperitoneum or pelvis.
Conditions Studied
Interventions
- PROCEDURE conventional surgery
- RADIATION radiation therapy
Study Locations (20)
Illinois
- Rush-Copley Cancer Care Center - Aurora
- Robert H. Lurie Comprehensive Cancer Center at Northwestern University - Chicago
- Joliet Oncology Hematology Associates, Limited - West - Joliet
- Cardinal Bernardin Cancer Center at Loyola University Medical Center - Maywood
- Saint James Hospital and Health Centers Comprehensive Cancer Institute - Olympia Fields - Olympia Fields
- Carle Cancer Center at Carle Foundation Hospital - Urbana
- CCOP - Carle Cancer Center - Urbana
Georgia
- Phoebe Cancer Center at Phoebe Putney Memorial Hospital - Albany
- Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center - Savannah
Indiana
- St. Francis Hospital and Health Centers - Beech Grove Campus - Beech Grove
- Saint Anthony Memorial Health Centers - Michigan City
Arkansas
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences - Little Rock
California
- City of Hope Comprehensive Cancer Center - Duarte
Colorado
- University of Colorado Cancer Center at University of Colorado Health Sciences Center - Aurora
District of Columbia
- George Washington University Medical Center - Washington D.C.
Florida
- University of Florida Shands Cancer Center - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 370 participants |
| Start Date | 2004-08 |
| Est. Completion | 2006-02 |
| Phase | Phase 3 |
What the finished NCT00091351 record still lists
NCT00091351 is an interventional study that assigns participants to a tested intervention. The registered 370 participants enrollment target is mid-sized for trials with a published cap, below the 918-participant average among 122 other Sarcoma trials with a reported enrollment target (60% lower).
The record links to 1 condition, with Sarcoma appearing as the primary indexed condition, and to 2 interventions - of which conventional surgery is the first listed.
NCT00091351 names 20 study sites across 12 states, led by Illinois, Georgia, Indiana.
Frequently Asked Questions
What is clinical trial NCT00091351 about?
NCT00091351 is a clinical study titled "Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis". RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation therapy before surgery may shrink the tumor so that it can be removed. It is not yet known whether surgery is more effective with or without radiation therapy. PURPOSE: This randomized phase III trial is st...
What is the current status of trial NCT00091351?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 370 participants. The study started on 2004-08. Estimated completion is 2006-02.
What conditions does trial NCT00091351 study?
This clinical trial studies the following conditions: Sarcoma.
What interventions are being tested in trial NCT00091351?
The interventions under investigation include: conventional surgery (PROCEDURE), radiation therapy (RADIATION).
Who is sponsoring clinical trial NCT00091351?
This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00091351 being conducted?
This trial has 20 study locations across Arkansas, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sarcoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00091351's enrollment target sits among peer trials
370 16th of 122 higher than 107 of 122 other Sarcoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sarcoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy
ACTIVE NOT RECRUITING · Phase 3
-
Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma
COMPLETED · Phase 3
-
A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families
COMPLETED · Phase 3
-
Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Cancer of the Uterus
COMPLETED · Phase 3
-
Comparison of Combination Chemotherapy Regimens in Treating Patients With Ewing's Sarcoma or Neuroectodermal Tumor
COMPLETED · Phase 3
-
Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer
COMPLETED · Phase 3
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02332668 · 370 participants · Phase 1
A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
- NCT04284436 · 370 participants · NA
Study in Parkinson Disease of Exercise
- NCT05026749 · 370 participants · Phase 3
Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children
- NCT05125016 · 370 participants · Phase 1
A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With Cemiplimab or REGN5678 for Adult Participants With Advanced Prostate Cancer
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia